B4222 Parenteral supply kit homemi

Parenteral nutrition supply kit; home mix, per day

Medically Unlikely Edits (effective October 1, 2026)

Medicare pricing for B4222

PEN fee schedule, January 2026 (DME26-A)

Payer policies and prior authorization for B4222

3 of 3 payer prior-auth lists that name B4222 require prior authorization or set conditions: Blue Cross and Blue Shield of Texas, Blue Shield of California, Passport by Molina Healthcare (Kentucky).

PayerPlanStatePrior authConditionsSinceSource
Blue Shield of CaliforniaBlue Shield commercialCAprior auth requiredSep 1, 2026Prior Authorization List for Blue Shield
Blue Cross and Blue Shield of TexasTexas PA exemption (gold card), outpatient, fully insuredTXprior auth requiredGold-card exemption availableJul 1, 2026BCBSTX Outpatient Prior Authorization Exemption Clinical Guidelines (max units, PA exempt date range)
Passport by Molina Healthcare (Kentucky)MedicaidKYprior auth under conditionsState exception; PA above 1 unit per calendar monthJul 1, 2026Kentucky Medicaid Prior Auth (PA) Code Matrix and Kentucky PA Code Exceptions, effective Q3 2026

Payer coverage policies that name B4222

B4222 appears in 12 coverage policies from Aetna, Anthem, Blue Cross & Blue Shield of Mississippi, Blue Cross Blue Shield of Massachusetts, BlueCross BlueShield of South Carolina, Centene, Health Care Service Corporation (BCBS IL, TX, OK, NM, MT), Molina Healthcare.

PayerPolicyRole in policyReviewedDocument
AetnaGrowth Hormone (GH) and Growth Hormone Antagonists (0170)listed, no stance (range B4164-B5200)Jun 26, 2026payer document
AetnaIntestinal Transplantation (0605)listed, no stance (range B4164-B5200)Sep 3, 2026payer document
AetnaNutritional Support (0061)
Enteral lactoferrin supplementation
covered if criteria are met (range B4102-B9999)Jan 15, 2026payer document
AetnaPediatric Intensive Feeding Programs (0809)listed, no stance (range B4164-B5200)Dec 11, 2025payer document
AnthemHome Parenteral Nutrition (CG-MED-89)covered if criteria are metMay 14, 2026payer document
AnthemIntradialytic Parenteral Nutrition (CG-MED-99)covered if criteria are metMay 14, 2026payer document
Blue Cross & Blue Shield of MississippiIntradialytic Parenteral Nutrition (L.8.01.413)covered if criteria are metpayer document
Blue Cross Blue Shield of MassachusettsTPN (296)listed, no stancepayer document
BlueCross BlueShield of South CarolinaIntradialytic Parenteral Nutrition (CAM 80144)listed, no stance (range B4164-B5200)Sep 1, 2026payer document
CenteneTotal Parenteral Nutrition and Intradialytic Parenteral Nutrition Reference Number: CP.MP.163 (CP.MP.163)covered if criteria are met (range B4164-B5200)Jan 1, 2026payer document
Health Care Service Corporation (BCBS IL, TX, OK, NM, MT)Nutritional Support (MED201.011)
HCPCS Codes B4034, B4035, B4036, B4081, B4082, B4083, B4087, B4088, B4102,
listed, no stanceJan 1, 2026payer document
Molina HealthcareRegulatory Statuslisted, no stancepayer document

Recent prior-auth changes

  • Jul 1, 2026: conditions changed, Passport by Molina Healthcare (Kentucky)
  • Oct 1, 2025: conditions changed, Passport by Molina Healthcare (Kentucky)
  • Jul 1, 2025: conditions changed, Passport by Molina Healthcare (Kentucky)

Medicaid fee-for-service

Prior authorization required or conditional in KY, MA, WY.

  • AZ: $19.53 (dme), effective Oct 1, 2026
  • IN: $12.18 (professional, Advanced Practice Nurse (85%), non-facility), effective Jan 1, 2026
  • KS: $8.16 (default), effective Jul 1, 2022
  • KY: $243.87 (dme), effective Jan 1, 2026
  • MA: $11.89 (dme_rates), effective Mar 1, 2026
  • MD: $9.44 (dme), effective Apr 1, 2026
  • MS: $10.91 (comprehensive), effective Jul 1, 2026
  • ND: $0.00 (dme), effective Aug 1, 2026
  • NE: $12.54 (dme), effective Jul 1, 2026
  • OH: $6.95 (dme), effective Jan 1, 2010
  • OK: $10.23 (dme), effective Jan 1, 2026
  • TX: $11.10 (dmepos_tos_9_e_j_l_and_r, Home Health Dme, non-facility), effective Jan 1, 2014
  • VT: $12.25 (outpatient_hospital_opps), effective Feb 1, 2026
  • WA: $10.98 (home_infusion_parenteral_nutrition), effective Jul 1, 2026
  • WY: $0.00 (outpatient_hospital_apc, Children's Hospitals), effective Apr 1, 2026

From payers' published prior-auth lists, coverage policies and state Medicaid fee schedules, updated Oct 16, 2026. The role is what the policy's own code table or text says about the code. Not a guarantee of coverage or payment; verify with the payer. CPT® is a registered trademark of the American Medical Association.