J0577 Inj, brixadi, 7 days or less

Injection, buprenorphine extended-release (brixadi), less than or equal to 7 days of therapy

Medically Unlikely Edits (effective October 1, 2026)

Medicare pricing for J0577

Medicare Part B drug payment limit (ASP, October 2026)

J0577 payment limit: $433.167 per Less than or equal to 7 days of therapy, effective October 1, 2026 through December 31, 2026, based on 2Q26 ASP data. Coinsurance 20%.

NDCs that bill under J0577 (CMS ASP NDC-HCPCS crosswalk, October 2026)

Physician Fee Schedule (CY 2026, RVU26D)

Status E: excluded from the PFS by regulation.

Payer policies and prior authorization for J0577

2 of 2 payer prior-auth lists that name J0577 require prior authorization or set conditions: Humana, Molina Healthcare of Mississippi.

PayerPlanStatePrior authConditionsSinceSource
HumanaHumana Healthy HorizonsINprior auth requiredOct 14, 2026Humana Healthy Horizons in Indiana prior authorization and notification list for provider-administered medications
Molina Healthcare of MississippiMedicaidMSprior auth requiredJan 1, 2025Mississippi Medicaid Prior Auth (PA) Code Matrix and exceptions, effective Q1 2025

Payer coverage policies that name J0577

J0577 appears in 5 coverage policies from Aetna, Centene, UnitedHealthcare.

PayerPolicyRole in policyReviewedDocument
AetnaExtended-Release Buprenorphine Injectables (0910)covered if criteria are metDec 30, 2025payer document
AetnaInjectable Medications (0020)listed, no stance (range J0278-J2543)Mar 5, 2026payer document
CenteneBuprenorphine Injection (Sublocade, Brixadi) (CP.PHAR.289)covered if criteria are metFeb 1, 2026payer document
UnitedHealthcareBuprenorphine (Brixadi® & Sublocade®) (2025D0057S)listed, no stanceNov 1, 2025payer document
UnitedHealthcareBuprenorphine (Brixadi® & Sublocade®) (CS2026D0057Y)listed, no stanceApr 1, 2026payer document

Recent prior-auth changes

  • Feb 1, 2026: PA added, Humana
  • Jan 1, 2026: PA added, Humana
  • Apr 1, 2025: PA removed, Molina Complete Care (Virginia)
  • Apr 1, 2025: PA removed, UnitedHealthcare
  • Mar 1, 2025: PA added, UnitedHealthcare
  • Apr 1, 2024: PA added, Molina Complete Care (Virginia)

Medicaid fee-for-service

Prior authorization required or conditional in IN.

  • AZ: $399.05 (asc), effective Oct 1, 2026
  • FL: $1.00 (physician_administered_drugs), effective Jan 1, 2026
  • IL: $417.21 (practitioner), effective Apr 1, 2026
  • IN: $396.27 (professional, Advanced Practice Nurse (85%), non-facility), effective Apr 1, 2026
  • KS: $433.17 (asc, facility), effective Oct 1, 2026
  • KY: $420.05 (asc), effective Jan 1, 2026
  • MS: $338.26 (comprehensive, facility), effective Oct 1, 2025
  • NE: $430.57 (injectables), effective Jul 1, 2026
  • OH: $417.21 (provider_administered_drugs), effective Jul 1, 2026
  • OK: $430.58 (physician, non-facility), effective Jul 1, 2026
  • TX: $420.05 (certified_nurse_midwife_cnm, Certified Nurse Midwife (Cnm), non-facility), effective Sep 1, 2026
  • VA: $430.57 (medical), effective Jul 1, 2026
  • VT: $319.69 (outpatient_hospital_opps), effective Feb 1, 2026
  • WA: $430.58 (professional_administered_drugs), effective Jul 1, 2026
  • WY: $180.59 (outpatient_hospital_apc, Ambulatory Surgical Centers), effective Apr 1, 2026

From payers' published prior-auth lists, coverage policies and state Medicaid fee schedules, updated Oct 16, 2026. The role is what the policy's own code table or text says about the code. Not a guarantee of coverage or payment; verify with the payer. CPT® is a registered trademark of the American Medical Association.