J0644 Inj, leucovorin cal (avyxa)

Injection, leucovorin calcium (avyxa), 1 mg

Medicare pricing for J0644

Medicare Part B drug payment limit (ASP, October 2026)

J0644 payment limit: $2.625 per 1 MG, effective October 1, 2026 through December 31, 2026, based on 2Q26 ASP data. Coinsurance 20%. Note: Added October 2026.

NDCs that bill under J0644 (CMS ASP NDC-HCPCS crosswalk, October 2026)

Physician Fee Schedule (CY 2026, RVU26D)

Status E: excluded from the PFS by regulation.

Payer policies and prior authorization for J0644

1 of 1 payer prior-auth lists that name J0644 require prior authorization or set conditions: HealthSpring.

PayerPlanStatePrior authConditionsSinceSource
HealthSpringMedicare AdvantageAllprior auth requiredOct 1, 20262026 Q4 Prior Authorization List

Payer coverage policies that name J0644

J0644 appears in 1 coverage policy from Aetna.

PayerPolicyRole in policyReviewedDocument
AetnaInjectable Medications (0020)listed, no stance (range J0278-J2543)Mar 5, 2026payer document

Recent prior-auth changes

  • Oct 1, 2026: PA added, HealthSpring
  • Nov 1, 2025: PA removed, UnitedHealthcare
  • Jan 1, 2025: PA added, UnitedHealthcare

From payers' published prior-auth lists, coverage policies and state Medicaid fee schedules, updated Oct 16, 2026. The role is what the policy's own code table or text says about the code. Not a guarantee of coverage or payment; verify with the payer. CPT® is a registered trademark of the American Medical Association.