J1000 Depo-estradiol cypionate inj

Injection, depo-estradiol cypionate, up to 5 mg

Medically Unlikely Edits (effective October 1, 2026)

Medicare pricing for J1000

Medicare Part B drug payment limit (ASP, October 2026)

J1000 payment limit: $53.805 per 5 MG, effective October 1, 2026 through December 31, 2026, based on 2Q26 ASP data. Coinsurance 20%.

NDCs that bill under J1000 (CMS ASP NDC-HCPCS crosswalk, October 2026)

Physician Fee Schedule (CY 2026, RVU26D)

Status E: excluded from the PFS by regulation.

Payer policies and prior authorization for J1000

9 of 9 payer prior-auth lists that name J1000 require prior authorization or set conditions: Molina Healthcare of Idaho, Molina Healthcare of Iowa, Molina Healthcare of Michigan, Molina Healthcare of Mississippi, Molina Healthcare of Utah, Passport by Molina Healthcare (Kentucky).

PayerPlanStatePrior authConditionsSinceSource
Molina Healthcare of IdahoIdaho state exceptions (exceptions only)IDprior auth under conditionsState exception; age under 18Jan 1, 2025Idaho code/benefit exceptions (Marketplace), Q1 2025
Molina Healthcare of IdahoMedicaidIDprior auth under conditionsState exception; age under 18Jan 1, 2025Idaho Medicaid Prior Auth (PA) Code Matrix and Idaho code/benefit exceptions, Q1 2025
Molina Healthcare of IowaMedicaidIAprior auth requiredJul 1, 2023IA Prior Authorization Matrix, effective Q3 2023
Molina Healthcare of MichiganMedicare AdvantageMIprior auth under conditionsage under 18Jul 1, 2026Molina Healthcare of Michigan PA Matrix 2026-Q3
Molina Healthcare of MississippiMississippi state exceptions (exceptions only)MSprior auth under conditionsState exception; age under 18Jan 1, 2025Mississippi code/benefit exceptions (Marketplace), 2025-Q1
Molina Healthcare of MississippiMedicaidMSprior auth under conditionsState exception; age under 18Jan 1, 2025Mississippi Medicaid Prior Auth (PA) Code Matrix and exceptions, effective Q1 2025
Molina Healthcare of UtahUtah state exceptions (exceptions only)UTprior auth requiredState exceptionJan 1, 2025Utah code/benefit exceptions (Marketplace), Q1 2025
Molina Healthcare of UtahMedicaidUTprior auth requiredState exceptionJan 1, 2025Utah Medicaid Prior Auth (PA) Code Matrix and Utah code/benefit exceptions, Q1 2025
Passport by Molina Healthcare (Kentucky)Kentucky state exceptions to the Molina Marketplace grid (exceptions only)KYprior auth requiredState exception; Medicaid: Not covered for certain indications as per House Bill 495Jul 1, 2026Kentucky Medicaid Prior Auth (PA) Code Matrix and Kentucky PA Code Exceptions, effective Q3 2026

Payer coverage policies that name J1000

J1000 appears in 4 coverage policies from Aetna.

PayerPolicyRole in policyReviewedDocument
AetnaAlzheimer's Disease: Experimental, Investigational, or Unproven Treatments (0788)not coveredNov 19, 2025payer document
AetnaGender Affirming Surgery (0615)covered if criteria are metSep 8, 2026payer document
AetnaInfertility (0327)covered if criteria are metJul 16, 2026payer document
AetnaInjectable Medications (0020)listed, no stance (range J0278-J2543)Mar 5, 2026payer document

Recent prior-auth changes

  • Apr 1, 2026: conditions changed, Passport by Molina Healthcare (Kentucky)
  • Jan 1, 2026: PA added, Molina Healthcare of Michigan
  • Nov 1, 2025: PA removed, UnitedHealthcare
  • Oct 1, 2025: PA removed, Passport by Molina Healthcare (Kentucky)
  • Jul 1, 2025: PA added, Passport by Molina Healthcare (Kentucky)
  • Apr 1, 2025: conditions changed, UnitedHealthcare
  • Mar 1, 2025: conditions changed, UnitedHealthcare
  • Jun 1, 2022: PA removed, Blue Shield of California Promise Health Plan

Medicaid fee-for-service

  • AZ: $53.81 (outpatient_hospital), effective Jul 1, 2026
  • FL: $1.00 (physician_administered_drugs), effective Jan 1, 2026
  • IL: $51.82 (practitioner), effective Apr 1, 2026
  • IN: $46.04 (professional, Advanced Practice Nurse (85%), non-facility), effective Apr 1, 2026
  • KS: $53.81 (default), effective Jul 1, 2026
  • KY: $0.00 (asc), effective Jan 1, 2026
  • MS: $51.82 (comprehensive), effective Jul 1, 2026
  • NE: $53.81 (injectables), effective Jul 1, 2026
  • OH: $51.82 (provider_administered_drugs), effective Jul 1, 2026
  • OK: $0.00 (outpatient_hospital_apc), effective Jan 1, 2026
  • TX: $16.80 (certified_nurse_midwife_cnm, Certified Nurse Midwife (Cnm), non-facility), effective Jan 1, 2018
  • VA: $53.81 (medical), effective Jul 1, 2026
  • VT: $0.00 (outpatient_hospital_opps), effective Feb 1, 2026
  • WA: $53.81 (professional_administered_drugs), effective Jul 1, 2026
  • WY: $0.00 (outpatient_hospital_apc, Children's Hospitals), effective Apr 1, 2026

From payers' published prior-auth lists, coverage policies and state Medicaid fee schedules, updated Oct 16, 2026. The role is what the policy's own code table or text says about the code. Not a guarantee of coverage or payment; verify with the payer. CPT® is a registered trademark of the American Medical Association.