J8705 Topotecan oral

Topotecan, oral, 0.25 mg

Medically Unlikely Edits (effective October 1, 2026)

Medicare pricing for J8705

Medicare Part B drug payment limit (ASP, October 2026)

J8705 payment limit: $125.461 per 0.25 mg, effective October 1, 2026 through December 31, 2026, based on 2Q26 ASP data. Coinsurance 20%.

NDCs that bill under J8705 (CMS ASP NDC-HCPCS crosswalk, October 2026)

Physician Fee Schedule (CY 2026, RVU26D)

Status E: excluded from the PFS by regulation.

Payer policies and prior authorization for J8705

1 of 1 payer prior-auth lists that name J8705 require prior authorization or set conditions: HealthSpring.

PayerPlanStatePrior authConditionsSinceSource
HealthSpringMedicare AdvantageAllprior auth requiredJan 1, 20252026 Q4 Prior Authorization List

Payer coverage policies that name J8705

J8705 appears in 3 coverage policies from Aetna, Centene.

PayerPolicyRole in policyReviewedDocument
AetnaAntiemetic Therapy (0724)listed, no stanceJul 17, 2026payer document
AetnaRevakinagene Taroretcel-lwey (Encelto) (1079)listed, no stance (range J8501-J9999)Oct 5, 2026payer document
CenteneTopotecan (Hycamtin) (CP.PHAR.64)covered if criteria are metMay 1, 2026payer document

Recent prior-auth changes

  • Jul 1, 2026: PA added, HealthSpring
  • Apr 1, 2025: PA removed, UnitedHealthcare
  • Mar 1, 2025: PA added, UnitedHealthcare
  • Jan 1, 2025: PA removed, UnitedHealthcare

Medicaid fee-for-service

Prior authorization required or conditional in IN.

  • AZ: $118.84 (asc), effective Oct 1, 2026
  • IL: $2880.15 (practitioner), effective Apr 1, 2026
  • KS: $125.46 (default), effective Oct 1, 2026
  • KY: $125.09 (asc), effective Jan 1, 2026
  • NE: $125.33 (injectables), effective Jul 1, 2026
  • OH: $125.22 (provider_administered_drugs), effective Jul 1, 2026
  • OK: $125.33 (physician, non-facility), effective Jul 1, 2026
  • VA: $125.33 (medical), effective Jul 1, 2026
  • VT: $0.00 (outpatient_hospital_opps), effective Feb 1, 2026
  • WA: $125.33 (professional_administered_drugs), effective Jul 1, 2026
  • WY: $54.20 (outpatient_hospital_apc, Ambulatory Surgical Centers), effective Apr 1, 2026

From payers' published prior-auth lists, coverage policies and state Medicaid fee schedules, updated Oct 16, 2026. The role is what the policy's own code table or text says about the code. Not a guarantee of coverage or payment; verify with the payer. CPT® is a registered trademark of the American Medical Association.