Q5168 Inj. nufymco, 0.1 mg

Injection, ranibizumab-leyk (nufymco), biosimilar, 0.1 mg

Medicare pricing for Q5168

Medicare Part B drug payment limit (ASP, October 2026)

Q5168 payment limit: $26.384 per 0.1 MG, effective October 1, 2026 through December 31, 2026, based on 2Q26 ASP data. Coinsurance 20%. Note: Added October 2026.

NDCs that bill under Q5168 (CMS ASP NDC-HCPCS crosswalk, October 2026)

Physician Fee Schedule (CY 2026, RVU26D)

Status E: excluded from the PFS by regulation.

Payer policies and prior authorization for Q5168

29 of 29 payer prior-auth lists that name Q5168 require prior authorization or set conditions: Aetna, Blue Cross Blue Shield of Arizona (AZ Blue), Blue Shield of California Promise Health Plan, CarePlus Health Plans, Cigna, HealthSpring, Humana, Molina Healthcare of Illinois, Passport by Molina Healthcare (Kentucky).

PayerPlanStatePrior authConditionsSinceSource
Blue Cross Blue Shield of Arizona (AZ Blue)AZ Blue-administered Medicare Advantage (M2K)AZprior auth requiredSep 1, 2026AZ Blue Medicare Advantage Prior Authorization Requirements Code List (Effective 09/01/2026)
Blue Cross Blue Shield of Arizona (AZ Blue)Standard PA code list (most commercial plans)AZprior auth requiredsite of care: site-of-service reviewSep 1, 2026AZ Blue Standard Prior Authorization Requirements Code List (09/01/2026)
Blue Cross Blue Shield of Arizona (AZ Blue)Standard PA code list (most commercial plans)AZprior auth requiredsite of care: site-of-service reviewSep 1, 2026AZ Blue Standard Prior Authorization Requirements Code List (09/01/2026)
Blue Cross Blue Shield of Arizona (AZ Blue)State of Arizona employee group (SYD, S3Z)AZprior auth requiredsite of care: site-of-service reviewSep 1, 2026State of Arizona Group Prior Authorization Requirements Code List (09/01/2026)
Blue Cross Blue Shield of Arizona (AZ Blue)Teamsters group (TYW)AZprior auth requiredSep 1, 2026Teamsters Group Prior Authorization Requirements Code List (Updated 09/01/2026)
Blue Shield of California Promise Health PlanPromise Health Plan Medi-CalCAprior auth requiredSep 1, 2026Medi-Cal Prior Authorization List
AetnaMedicare AdvantageAllprior auth requiredAug 25, 2026Aetna Medicare Part B drug list (partbname.xml)
AetnaMedicare AdvantageAllprior auth requiredMay 1, 2026Participating provider precertification list for Aetna®
AetnaCommercialAllprior auth requiredMay 1, 2026Participating provider precertification list for Aetna®
CignaACA/IFPAllprior auth requiredJul 1, 2026Master Precertification List (For Health Care Providers)
CignaBasic StandardAllprior auth requiredJul 1, 2026Master Precertification List (For Health Care Providers)
CignaComplete/PHS+/PreferredAllprior auth requiredJul 1, 2026Master Precertification List (For Health Care Providers)
HealthSpringMedicare AdvantageAllprior auth requiredAug 1, 20262026 Q4 Prior Authorization List
CarePlus Health PlansCarePlus Health PlansFLprior auth requiredStep therapyJan 1, 2027Medicare Advantage and Dual Eligible Special Needs Plans Prior Authorization and Notification List We have updated our CarePlus Health Plans Prior Authorization and Notification List for CarePlus Medi
HumanaHumana D-SNP (FL)FLprior auth requiredNew PA requirement; Step therapyJul 1, 2026H1036-280 Humana Fully Integrated Florida prior authorization and notification list
HumanaHumana D-SNP (IL)ILprior auth requiredStep therapyJan 1, 2027Humana Dual Fully Integrated Illinois prior authorization and notification list
HumanaHumana D-SNP (IN)INprior auth requiredStep therapyJan 1, 2027Humana PathWays Dual Care (HMO-POS D-SNP) prior authorization and notification list Important notes:
HumanaHumana D-SNP (MI)MIprior auth requiredNew PA requirement; Step therapyOct 14, 2026Humana Dual Integrated (health maintenance organization Dual Eligible Special Needs Plan (HMO D- SNP) Michigan prior authorization and notification list (PAL)
HumanaHumana D-SNP (SC)SCprior auth requiredNew PA requirement; Step therapyJul 1, 2026Humana Dual Integrated South Carolina prior authorization and notification list
HumanaHumana D-SNP (VA)VAprior auth requiredNew PA requirement; Step therapyJul 1, 2026Prior authorization and notification list Humana Dual Fully Integrated H2875-001 (Virginia) Humana Dual Fully Integrated H2875-003 (Virginia)
HumanaHumana Healthy HorizonsKYprior auth requiredOct 7, 2026Humana Healthy Horizons in Kentucky Prior Authorization and Notification List
HumanaHumana Healthy HorizonsLAprior auth requiredOct 14, 2026Humana Healthy Horizons in Louisiana Prior Authorization and Notification List
HumanaHumana Healthy HorizonsOHprior auth requiredOct 14, 2026Humana Healthy Horizons in Ohio prior authorization and notification List
HumanaHumana Healthy HorizonsOKprior auth requiredOct 14, 2026Humana Healthy Horizons in Oklahoma Prior Authorization and Notification List
HumanaHumana Healthy HorizonsSCprior auth requiredOct 14, 2026Humana Healthy Horizons in South Carolina prior authorization and notification list
HumanaHumana Healthy HorizonsVAprior auth requiredOct 14, 2026Humana Healthy Horizons in Virginia professionally administered medication prior authorization and notification list
HumanaHumana MA and D-SNPAllprior auth requiredStep therapyJan 1, 2027Medicare Advantage and Dual Eligible Special Needs Plans prior authorization and notification list Important notes:
Molina Healthcare of IllinoisMedicaidILprior auth requiredJul 1, 2026Molina Healthcare of Illinois Codification Grid Q3 2026
Passport by Molina Healthcare (Kentucky)MedicaidKYprior auth requiredJul 1, 2026Kentucky Medicaid Prior Auth (PA) Code Matrix and Kentucky PA Code Exceptions, effective Q3 2026

Payer coverage policies that name Q5168

Q5168 appears in 7 coverage policies from Aetna, Centene, Premera Blue Cross, UnitedHealthcare, Wellmark Blue Cross Blue Shield.

PayerPolicyRole in policyReviewedDocument
AetnaDexamethasone Ophthalmic Implant (Ozurdex) and Insert (Dextenza) (0795)listed, no stanceOct 5, 2026payer document
AetnaRevakinagene Taroretcel-lwey (Encelto) (1079)listed, no stanceOct 5, 2026payer document
AetnaVascular Endothelial Growth Factor Inhibitors for Ocular Indications (0701)covered if criteria are metOct 5, 2026payer document
CenteneRanibizumab (Byooviz, Cimerli, Lucentis, Nufymco, Ranluspec, Susvimo) (CP.PHAR.186)covered if criteria are metFeb 1, 2026payer document
Premera Blue Cross(effective January 1, 2027) Vascular Endothelial Growth Factor (VEGF) Receptor Inhibitors for Ocular Disorders (5.01.620)
Page | 7 of 20 | ∞
listed, no stanceSep 8, 2026payer document
UnitedHealthcareOphthalmologic Vascular Endothelial Growth Factor (VEGF) Inhibitors (2026D0042AQ)listed, no stanceJul 1, 2026payer document
Wellmark Blue Cross Blue ShieldVascular Endothelial Growth Factor (VEGF) Inhibitors for Ophthalmic Use (09.03.12)listed, no stanceOct 1, 2025payer document

Recent prior-auth changes

  • Oct 14, 2026: PA removed, Humana
  • Sep 1, 2026: PA added, Blue Shield of California Promise Health Plan
  • Aug 1, 2026: PA removed, Blue Shield of California Promise Health Plan
  • Aug 1, 2026: PA added, HealthSpring
  • Jul 1, 2026: PA added, CarePlus Health Plans
  • Jul 1, 2026: PA added, Humana
  • Jul 1, 2026: PA added, Passport by Molina Healthcare (Kentucky)
  • Jul 1, 2026: PA added, Blue Shield of California Promise Health Plan
  • Jul 1, 2026: PA added, Molina Healthcare of Illinois
  • May 1, 2026: PA added, Aetna

Medicaid fee-for-service

  • AZ: $269.33 (outpatient_hospital), effective Jul 1, 2026
  • IL: $257.74 (practitioner), effective Jul 1, 2026
  • KS: $19.79 (default, Exempt Physician), effective Oct 1, 2026
  • NE: $287.64 (injectables), effective Jul 1, 2026
  • OK: $269.60 (physician, non-facility), effective Jul 1, 2026
  • VT: $0.00 (outpatient_hospital_opps), effective Jul 1, 2026

From payers' published prior-auth lists, coverage policies and state Medicaid fee schedules, updated Oct 16, 2026. The role is what the policy's own code table or text says about the code. Not a guarantee of coverage or payment; verify with the payer. CPT® is a registered trademark of the American Medical Association.