S2142 Cord blood-derived stem-cellCord blood-derived stem-cell transplantation, allogeneic
Status I: not valid for Medicare (Medicare uses another code).
39 of 40 payer prior-auth lists that name S2142 require prior authorization or set conditions: Blue Cross Blue Shield of Arizona (AZ Blue), Blue Cross and Blue Shield of Texas, Cigna, Humana, Molina Complete Care (Virginia), Molina Healthcare of California, Molina Healthcare of Idaho, Molina Healthcare of Illinois, Molina Healthcare of Iowa, Molina Healthcare of Michigan, Molina Healthcare of Mississippi, Molina Healthcare of Nevada, Molina Healthcare of New Mexico, Molina Healthcare of Ohio, Molina Healthcare of Texas, Molina Healthcare of Utah, Neighborhood Health Partnership, Oxford Health Plans, Passport by Molina Healthcare (Kentucky), Rocky Mountain Health Plans, and others.
S2142 appears in 103 coverage policies from Aetna, Anthem, Blue Cross & Blue Shield of Mississippi, Blue Cross Blue Shield of Massachusetts, Blue Shield of California, BlueCross BlueShield of South Carolina, Capital Blue Cross, Centene, Cigna, Health Care Service Corporation (BCBS IL, TX, OK, NM, MT), Premera Blue Cross, Regence.
| Payer | Policy | Role in policy | Reviewed | Document |
|---|---|---|---|---|
| Aetna | Afamitresgene Autoleucel (Tecelra) (1068) | listed, no stance | Jan 14, 2026 | payer document |
| Aetna | Bone and Tendon Graft Substitutes and Adjuncts (0411) | not covered | Aug 18, 2026 | payer document |
| Aetna | Epilepsy Surgery (0394) | not covered | Jun 23, 2026 | payer document |
| Aetna | Erythropoiesis Stimulating Agents (0195) | not covered | Jan 20, 2026 | payer document |
| Aetna | Hematopoietic Cell Transplantation for Autoimmune Diseases and Miscellaneous Indications (0606) | not covered | Sep 18, 2026 | payer document |
| Aetna | Hematopoietic Cell Transplantation for Inherited Metabolic Disorders and Genetic Diseases (0871) | covered if criteria are met | Dec 22, 2025 | payer document |
| Aetna | Hematopoietic Cell Transplantation for Solid Tumors in Adults (0811) | not covered | Dec 3, 2025 | payer document |
| Aetna | Intradiscal Procedures (0602) | not covered | Sep 2, 2026 | payer document |
| Aetna | Narsoplimab-wuug (Yartemlea) (1099) | listed, no stance | Apr 27, 2026 | payer document |
| Aetna | Omidubicel-onlv (Omisirge) (1032) | listed, no stance | Apr 27, 2026 | payer document |
| Aetna | Pegzilarginase-nbln (Loargys) (1101) | listed, no stance | Jun 26, 2026 | payer document |
| Aetna | Stem Cells for Hematopoietic Cell Transplant (0190) | covered if criteria are met | Mar 27, 2026 | payer document |
| Anthem | Hematopoietic Stem Cell Transplantation for Autoimmune Disease and Miscellaneous Solid Tumors (TRANS.00031) | unproven / investigational | May 14, 2026 | payer document |
| Anthem | Hematopoietic Stem Cell Transplantation for Diabetes Mellitus (TRANS.00034) | unproven / investigational | Nov 6, 2025 | payer document |
| Anthem | Hematopoietic Stem Cell Transplantation for Genetic Diseases and Aplastic Anemias (TRANS.00029) | covered if criteria are met | Nov 6, 2025 | payer document |
| Anthem | Hematopoietic Stem Cell Transplantation for Germ Cell Tumors (TRANS.00030) | unproven / investigational | Nov 6, 2025 | payer document |
| Anthem | Hematopoietic Stem Cell Transplantation for Hodgkin Disease and non-Hodgkin Lymphoma (TRANS.00028) | covered if criteria are met | May 14, 2026 | payer document |
| Anthem | Hematopoietic Stem Cell Transplantation for Multiple Myeloma and Other Plasma Cell Dyscrasias (TRANS.00023) | covered if criteria are met | Nov 6, 2025 | payer document |
| Anthem | Hematopoietic Stem Cell Transplantation for Pediatric Solid Tumors (TRANS.00027) | covered if criteria are met | Nov 6, 2025 | payer document |
| Anthem | Hematopoietic Stem Cell Transplantation for Select Leukemias and Myelodysplastic Syndrome (TRANS.00024) | covered if criteria are met | Nov 6, 2025 | payer document |
| Blue Cross & Blue Shield of Mississippi | Hematopoietic Cell Transplantation For Acute Lymphoblastic Leukemia To report antineoplastic drugs, see code range J9000 - J9999 in the HCPCS Level II manual. | covered if criteria are met | payer document | |
| Blue Cross & Blue Shield of Mississippi | Hematopoietic Cell Transplantation For Acute Myeloid Leukemia To report antineoplastic drugs, see code range J9000-J9999 in the HCPCS Level II manual. | covered if criteria are met | payer document | |
| Blue Cross & Blue Shield of Mississippi | Hematopoietic Cell Transplantation For Chronic Lymphocytic Leukemiasmall Lymphocytic Lymphoma HCPCS - To report antineoplastic drugs, see code range J9000-J9999 in the HCPCS Level II manual. | covered if criteria are met | payer document | |
| Blue Cross & Blue Shield of Mississippi | Hematopoietic Cell Transplantation For Chronic Myeloid Leukemia | covered if criteria are met | payer document | |
| Blue Cross & Blue Shield of Mississippi | Hematopoietic Cell Transplantation For Cns Embryonal Tumors And Ependymoma | unproven / investigational | payer document | |
| Blue Cross & Blue Shield of Mississippi | Hematopoietic Cell Transplantation For Epithelial Ovarian Cancer To report antineoplastic drugs, see code range J9000-J9999 in the HCPCS Level II manual. | unproven / investigational | payer document | |
| Blue Cross & Blue Shield of Mississippi | Hematopoietic Cell Transplantation For Miscellaneous Solid Tumors In Adults To report antineoplastic drugs, see code range J9000-J9999 in the HCPCS Level II manual. | unproven / investigational | payer document | |
| Blue Cross & Blue Shield of Mississippi | Hematopoietic Cell Transplantation In The Treatment Of Germ Cell Tumors | unproven / investigational | payer document | |
| Blue Cross & Blue Shield of Mississippi | Nonmyeloablative Allogeneic Transplants Of Hematopoietic Stemcells For Treatment Of Malignancy (L.8.01.406) To report antineoplastic drugs, see code range J9000-J9999 in the HCPCS Level II manual | covered if criteria are met | payer document | |
| Blue Cross & Blue Shield of Mississippi | Placental And Umbilical Cord Blood As A Source Of Stem Cells (L.7.01.442) | covered if criteria are met | payer document | |
| Blue Cross Blue Shield of Massachusetts | Allogeneic Hematopoietic Stem Cell Transplantation for Genetic Disease and Acquired Anemias (190) | listed, no stance | payer document | |
| Blue Cross Blue Shield of Massachusetts | Hematopoietic Cell Transplantation (076) | listed, no stance | payer document | |
| Blue Cross Blue Shield of Massachusetts | Hematopoietic Cell Transplantation for Acute Myeloid Leukemia (150) | listed, no stance | payer document | |
| Blue Cross Blue Shield of Massachusetts | Hematopoietic Cell Transplantation for Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma (074) | listed, no stance | payer document | |
| Blue Cross Blue Shield of Massachusetts | Hematopoietic Cell Transplantation for Chronic Myeloid Leukemia (212) | listed, no stance | payer document | |
| Blue Cross Blue Shield of Massachusetts | Hematopoietic Cell Transplantation for Hodkin Lymphoma (207) | listed, no stance | payer document | |
| Blue Cross Blue Shield of Massachusetts | Hematopoietic Cell Transplantation for Multiple Myeloma (075) | unproven / investigational | payer document | |
| Blue Cross Blue Shield of Massachusetts | Hematopoietic Cell Transplantation for Non-Hodgkin Lymphomas (143) | listed, no stance | payer document | |
| Blue Cross Blue Shield of Massachusetts | Hematopoietic Cell Transplantation for Solid Tumors of Childhood (208) | unproven / investigational | payer document | |
| Blue Cross Blue Shield of Massachusetts | Hematopoietic Cell Transplantation fr Epithelial Ovarian Cancer (204) | unproven / investigational | payer document | |
| Blue Cross Blue Shield of Massachusetts | Hematopoietic Cell Transplantation in the Treatment of Germ Cell Tumors (247) | unproven / investigational | payer document | |
| Blue Cross Blue Shield of Massachusetts | Hematopoietic Stem-Cell Transplantation for Waldenstrom Macroglobulinemia (322) | unproven / investigational | payer document | |
| Blue Cross Blue Shield of Massachusetts | hematopoietic Cell Transplantation for Miscellaneous Solid Tumors in Adults (191) | unproven / investigational | payer document | |
| Blue Shield of California | Hematopoietic Cell Transplantation for Acute Lymphoblastic Leukemia (8.01.32) | listed, no stance | payer document | |
| Blue Shield of California | Hematopoietic Cell Transplantation for Acute Myeloid Leukemia (8.01.26) | listed, no stance | payer document | |
| Blue Shield of California | Hematopoietic Cell Transplantation for Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (8.01.15) | listed, no stance | payer document | |
| Blue Shield of California | Hematopoietic Cell Transplantation for Chronic Myeloid Leukemia (8.01.30) | listed, no stance | payer document | |
| Blue Shield of California | Hematopoietic Cell Transplantation for Epithelial Ovarian Cancer (8.01.23) | listed, no stance | payer document | |
| Blue Shield of California | Hematopoietic Cell Transplantation for Hodgkin Lymphoma (8.01.29) | listed, no stance | payer document | |
| Blue Shield of California | Hematopoietic Cell Transplantation for Non-Hodgkin Lymphomas (8.01.20) | listed, no stance | payer document | |
| Blue Shield of California | Hematopoietic Cell Transplantation for Plasma Cell Dyscrasias, Including Multiple Myeloma and POEMS Syndrome (8.01.17) | listed, no stance | payer document | |
| Blue Shield of California | Hematopoietic Cell Transplantation for Primary Amyloidosis (8.01.42) | listed, no stance | payer document | |
| Blue Shield of California | Hematopoietic Cell Transplantation for Solid Tumors of Childhood (8.01.34) | listed, no stance | payer document | |
| Blue Shield of California | Hematopoietic Cell Transplantation in the Treatment of Germ Cell Tumors (8.01.35) | listed, no stance | payer document | |
| BlueCross BlueShield of South Carolina | Hematopoietic Cell Transplantation for Breast Cancer (CAM 80127) | listed, no stance | Jul 1, 2026 | payer document |
| BlueCross BlueShield of South Carolina | Hematopoietic Stem-Cell Transplantation for Plasma Cell Dyscrasias, Including Multiple Myeloma and POEMS Syndrome (CAM 80117) | listed, no stance | Jan 1, 2026 | payer document |
| Capital Blue Cross | Hematopoietic Cell Transplantation for Acute Lymphoblastic Leukemia (MP 9.041) Procedure codes | covered if criteria are met | Sep 1, 2026 | payer document |
| Capital Blue Cross | Hematopoietic Cell Transplantation for Acute Myeloid Leukemia (MP 9.040) Procedure codes | covered if criteria are met | May 1, 2026 | payer document |
| Capital Blue Cross | Hematopoietic Cell Transplantation for Autoimmune diseases (MP 9.053) Procedure codes | unproven / investigational | Sep 1, 2026 | payer document |
| Capital Blue Cross | Hematopoietic Cell Transplantation for Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma (MP 9.038) Procedure codes | covered if criteria are met | Sep 1, 2026 | payer document |
| Capital Blue Cross | Hematopoietic Cell Transplantation for Chronic Myeloid Leukemia (MP 9.039) Procedure codes | covered if criteria are met | Sep 1, 2026 | payer document |
| Capital Blue Cross | Hematopoietic Cell Transplantation for Epithelial Ovarian Cancer (MP 9.047) Procedure codes | unproven / investigational | May 1, 2026 | payer document |
| Capital Blue Cross | Hematopoietic Cell Transplantation for Miscellaneous Solid Tumors in Adults (MP 9.048) Procedure codes | unproven / investigational | May 1, 2026 | payer document |
| Capital Blue Cross | Hematopoietic Cell Transplantation for Non-Hodgkin Lymphomas (MP 9.042) Procedure Codes | covered if criteria are met | Sep 1, 2026 | payer document |
| Capital Blue Cross | Hematopoietic Cell Transplantation for Primary Amyloidosis (MP 9.045) Procedure codes | unproven / investigational | May 1, 2026 | payer document |
| Capital Blue Cross | Hematopoietic Cell Transplantation for Solid Tumors of Childhood (MP 9.054) Procedure Codes | unproven / investigational | Sep 1, 2026 | payer document |
| Centene | Nonmyeloablative Allogeneic Stem Cell Transplants Reference Number: CP.MP.141 (CP.MP.141) | covered if criteria are met | Jan 1, 2026 | payer document |
| Cigna | Stem Cell Transplantation: Blood Cancers (0533) | covered if criteria are met | Aug 15, 2026 | payer document |
| Cigna | Stem Cell Transplantation: Non-Cancer Disorders (0535) | covered if criteria are met | Jan 15, 2026 | payer document |
| Cigna | Stem Cell Transplantation: Solid Tumors (0534) | covered if criteria are met | Jan 15, 2026 | payer document |
| Health Care Service Corporation (BCBS IL, TX, OK, NM, MT) | Allogeneic Hematopoietic Cell Transplantation for Myelodysplastic Syndromes and Myeloproliferative Neoplasms (SUR703.032) CPT Codes 36511, 38204, 38205, 38206, 38207, 38208, 38209, 38210, 38211, | listed, no stance | May 15, 2026 | payer document |
| Health Care Service Corporation (BCBS IL, TX, OK, NM, MT) | Hematopoietic Cell Transplantation for Acute Lymphoblastic Leukemia (SUR703.043) CPT Codes 36511, 38204, 38205, 38206, 38207, 38208, 38209, 38210, 38211, 38212, | listed, no stance | Sep 1, 2026 | payer document |
| Health Care Service Corporation (BCBS IL, TX, OK, NM, MT) | Hematopoietic Cell Transplantation for Acute Myeloid Leukemia (SUR703.037) CPT Codes 36511, 38204, 38205, 38206, 38207, 38208, 38209, 38210, 38211, 38212, | listed, no stance | Aug 15, 2026 | payer document |
| Health Care Service Corporation (BCBS IL, TX, OK, NM, MT) | Hematopoietic Cell Transplantation for Autoimmune Diseases (SUR703.036) CPT Codes 36511, 38204, 38205, 38206, 38207, 38208, 38209, 38210, 38211, | listed, no stance | Jun 15, 2026 | payer document |
| Health Care Service Corporation (BCBS IL, TX, OK, NM, MT) | Hematopoietic Cell Transplantation for Breast Cancer (SUR703.038) CPT Codes 36511, 38204, 38205, 38206, 38207, 38208, 38209, 38210, 38211, | listed, no stance | May 1, 2026 | payer document |
| Health Care Service Corporation (BCBS IL, TX, OK, NM, MT) | Hematopoietic Cell Transplantation for Central Nervous System Embryonal Tumors and Ependymoma (SUR703.039) CPT Codes 36511, 38204, 38205, 38206, 38207, 38208, 38209, 38210, 38211, | listed, no stance | Sep 1, 2026 | payer document |
| Health Care Service Corporation (BCBS IL, TX, OK, NM, MT) | Hematopoietic Cell Transplantation for Chronic Lymphocytic Leukemia (CLL) and Small Lymphocytic Lymphoma (SLL) (SUR703.029) CPT Codes 36511, 38204, 38205, 38206, 38207, 38208, 38209, 38210, 38211, 38212, | listed, no stance | May 15, 2026 | payer document |
| Health Care Service Corporation (BCBS IL, TX, OK, NM, MT) | Hematopoietic Cell Transplantation for Chronic Myeloid Leukemia (SUR703.041) CPT Codes 36511, 38204, 38205, 38206, 38207, 38208, 38209, 38210, 38211, 38212, | listed, no stance | Jun 15, 2026 | payer document |
| Health Care Service Corporation (BCBS IL, TX, OK, NM, MT) | Hematopoietic Cell Transplantation for Epithelial Ovarian Cancer (SUR703.034) CPT Codes 36511, 38204, 38205, 38206, 38207, 38208, 38209, 38210, 38211, | listed, no stance | May 1, 2026 | payer document |
| Health Care Service Corporation (BCBS IL, TX, OK, NM, MT) | Hematopoietic Cell Transplantation for Genetic Diseases and Acquired Anemias (SUR703.033) CPT Codes 36511, 38204, 38205, 38206, 38207, 38208, 38209, 38210, 38211, | listed, no stance | Jun 15, 2026 | payer document |
| Health Care Service Corporation (BCBS IL, TX, OK, NM, MT) | Hematopoietic Cell Transplantation for Hodgkin Lymphoma (SUR703.040) CPT Codes 36511, 38204, 38205, 38206, 38207, 38208, 38209, 38210, 38211, 38212, | listed, no stance | Apr 15, 2026 | payer document |
| Health Care Service Corporation (BCBS IL, TX, OK, NM, MT) | Hematopoietic Cell Transplantation for Miscellaneous Solid Tumors in Adults (SUR703.035) CPT Codes 36511, 38204, 38205, 38206, 38207, 38208, 38209, 38210, 38211, 38212, | listed, no stance | Aug 15, 2026 | payer document |
| Health Care Service Corporation (BCBS IL, TX, OK, NM, MT) | Hematopoietic Cell Transplantation for Non-Hodgkin Lymphomas (SUR703.031) CPT Codes 36511, 38204, 38205, 38206, 38207, 38208, 38209, 38210, 38211, 38212, | listed, no stance | May 1, 2026 | payer document |
| Health Care Service Corporation (BCBS IL, TX, OK, NM, MT) | Hematopoietic Cell Transplantation for Plasma Cell Dyscrasias, Including Multiple Myeloma and POEMS Syndrome (SUR703.030) CPT Codes 36511, 38204, 38205, 38206, 38207, 38208, 38209, 38210, 38211, 38212, | listed, no stance | May 1, 2026 | payer document |
| Health Care Service Corporation (BCBS IL, TX, OK, NM, MT) | Hematopoietic Cell Transplantation for Primary Systemic Amyloidosis (SUR703.046) CPT Codes 36511, 38204, 38205, 38206, 38207, 38208, 38209, 38210, 38211, 38212, | listed, no stance | Jun 15, 2026 | payer document |
| Health Care Service Corporation (BCBS IL, TX, OK, NM, MT) | Hematopoietic Cell Transplantation for Solid Tumors of Childhood (SUR703.044) CPT Codes 36511, 38204, 38205, 38206, 38207, 38208, 38209, 38210, 38211, | listed, no stance | Jun 15, 2026 | payer document |
| Health Care Service Corporation (BCBS IL, TX, OK, NM, MT) | Hematopoietic Cell Transplantation for Waldenstrom Macroglobulinemia (SUR703.050) CPT Codes 36511, 38204, 38205, 38206, 38207, 38208, 38209, 38210, 38211, | listed, no stance | Jan 1, 2026 | payer document |
| Health Care Service Corporation (BCBS IL, TX, OK, NM, MT) | Hematopoietic Cell Transplantation in the Treatment of Germ Cell Tumors (SUR703.045) CPT Codes 36511, 38204, 38205, 38206, 38207, 38208, 38209, 38210, 38211, | listed, no stance | Jun 15, 2026 | payer document |
| Premera Blue Cross | Allogeneic Hematopoietic Cell Transplantation for Myelodysplastic Syndromes and Myeloproliferative Neoplasms (8.01.539) | listed, no stance | Mar 23, 2026 | payer document |
| Premera Blue Cross | Hematopoietic Cell Transplantation for Acute Lymphoblastic Leukemia (8.01.520) Page | 3 of 19 | ∞ | listed, no stance | Mar 23, 2026 | payer document |
| Premera Blue Cross | Hematopoietic Cell Transplantation for Acute Myeloid Leukemia (8.01.542) | listed, no stance | Apr 14, 2026 | payer document |
| Premera Blue Cross | Hematopoietic Cell Transplantation for Autoimmune Diseases (8.01.25) | listed, no stance | Jul 14, 2026 | payer document |
| Premera Blue Cross | Hematopoietic Cell Transplantation for Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma (8.01.15) | listed, no stance | Mar 9, 2026 | payer document |
| Premera Blue Cross | Hematopoietic Cell Transplantation for Chronic Myeloid Leukemia (8.01.30) | listed, no stance | Mar 9, 2026 | payer document |
| Premera Blue Cross | Hematopoietic Cell Transplantation for Epithelial Ovarian Cancer (8.01.23) | listed, no stance | Mar 9, 2026 | payer document |
| Premera Blue Cross | Hematopoietic Cell Transplantation for Hodgkin Lymphoma (8.01.29) | listed, no stance | Mar 23, 2026 | payer document |
| Premera Blue Cross | Hematopoietic Cell Transplantation for Miscellaneous Solid Tumors in Adults (8.01.24) | listed, no stance | Mar 9, 2026 | payer document |
| Premera Blue Cross | Hematopoietic Cell Transplantation for Non-Hodgkin Lymphomas (8.01.529) | listed, no stance | Mar 9, 2026 | payer document |
| Premera Blue Cross | Hematopoietic Cell Transplantation for Plasma Cell Dyscrasias, Including Multiple Myeloma and POEMS Syndrome (8.01.17) | listed, no stance | Mar 9, 2026 | payer document |
| Premera Blue Cross | Hematopoietic Cell Transplantation for Primary Amyloidosis (8.01.42) | listed, no stance | Mar 9, 2026 | payer document |
Prior authorization required or conditional in CO, IN.
From payers' published prior-auth lists, coverage policies and state Medicaid fee schedules, updated Oct 16, 2026. The role is what the policy's own code table or text says about the code. Not a guarantee of coverage or payment; verify with the payer. CPT® is a registered trademark of the American Medical Association.