S3849 Gene test niemann-pick

Genetic testing for niemann-pick disease

Medicare pricing for S3849

Physician Fee Schedule (CY 2026, RVU26D)

Status I: not valid for Medicare (Medicare uses another code).

Payer policies and prior authorization for S3849

2 of 2 payer prior-auth lists that name S3849 require prior authorization or set conditions: Blue Cross and Blue Shield of Texas, Humana.

PayerPlanStatePrior authConditionsSinceSource
Blue Cross and Blue Shield of TexasTexas PA exemption (gold card), outpatient, fully insuredTXprior auth requiredGold-card exemption availableApr 1, 2024BCBSTX Outpatient Prior Authorization Exemption Clinical Guidelines (max units, PA exempt date range)
HumanaOak Street HealthAllprior auth requiredOak Street Health (Humana): Prior Authorization List (PAL) Codes Under Management

Payer coverage policies that name S3849

S3849 appears in 6 coverage policies from Aetna, Blue Cross & Blue Shield of Mississippi, Blue Cross Blue Shield of Massachusetts, Regence.

PayerPolicyRole in policyReviewedDocument
AetnaInvasive Prenatal Diagnosis of Genetic Diseases (0358)listed, no stance (range S3841-S3853)May 22, 2026payer document
AetnaRecurrent Pregnancy Loss (0348)
Other HCPCS related to the CPB
covered if criteria are met (range S3800-S3870)Jun 23, 2026payer document
Blue Cross & Blue Shield of MississippiGenetic Testing (L.2.04.409)covered if criteria are metpayer document
Blue Cross Blue Shield of MassachusettsCarelon Genetic Testing Management Program CPT and HCPCS Codes (957)listed, no stancepayer document
RegenceGenetic and Molecular Diagnostic Testing (Genetic Testing 20)listed, no stanceApr 1, 2025payer document
RegenceReproductive Carrier Screening for Genetic Diseases (Genetic Testing 81)listed, no stanceOct 1, 2025payer document

Recent prior-auth changes

  • Mar 1, 2025: PA removed, Rocky Mountain Health Plans
  • Mar 1, 2025: PA removed, Rocky Mountain Health Plans

Medicaid fee-for-service

Prior authorization required or conditional in IN.

  • CO: $156.38 (health_first_colorado), effective Jul 1, 2026
  • ND: $0.00 (physician), effective Aug 1, 2026

From payers' published prior-auth lists, coverage policies and state Medicaid fee schedules, updated Oct 16, 2026. The role is what the policy's own code table or text says about the code. Not a guarantee of coverage or payment; verify with the payer. CPT® is a registered trademark of the American Medical Association.