B45.1 Cerebral cryptococcosis

Billable ICD-10-CM code, FY2026. Acts as a Major Complication or Comorbidity (MCC) as a secondary diagnosis.

Applicable to

• Cryptococcal meningitis
• Cryptococcosis meningocerebralis

Risk adjustment (HCC)

• CMS-HCC V28: HCC 6 — Opportunistic Infections
• CMS-HCC V22: HCC 6 — Opportunistic Infections
• RxHCC V08: HCC 5 — Opportunistic Infections
• ESRD V24: HCC 6

MS-DRG index

Defines the logic of DRG(s) 023-024 in MDC 01.

Approximate ICD-9-CM (GEMs)

• 117.5 Cryptococcosis (approximate)
• 321.0 Cryptococcal meningitis (approximate)

Code annotations containing back-references to B45.1

Back-references to B45.1

• Type 1 Excludes: G02 Meningitis in other infectious and parasitic diseases classified elsewhere ("cryptococcal meningitis (B45.1)")

Back-references to B45

• Code First: M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere ("mycoses (B35-B49)")

Diagnosis Index entries for B45.1

• Cryptococcosis, cryptococcus (infection) (neoformans) › cerebral
• Cryptococcosis, cryptococcus (infection) (neoformans) › meningitis
• Cryptococcosis, cryptococcus (infection) (neoformans) › meningocerebralis
• Encephalitis (chronic) (hemorrhagic) (idiopathic) (nonepidemic) (spurious) (subacute) › Torula, torular (cryptococcal)
• Meningitis (basal) (basic) (brain) (cerebral) (cervical) (congestive) (diffuse) (hemorrhagic) (infantile) (membranous) (metastatic) (nonspecific) (pontine) (progressive) (simple) (spinal) (subacute) (sympathetic) (toxic) › cryptococcal
• Meningitis (basal) (basic) (brain) (cerebral) (cervical) (congestive) (diffuse) (hemorrhagic) (infantile) (membranous) (metastatic) (nonspecific) (pontine) (progressive) (simple) (spinal) (subacute) (sympathetic) (toxic) › Torula histolytica (cryptococcal)
• Meningoencephalomyelitis › due to › Torula
• Meningomyelitis › cryptococcal

Nearby codes

• B45 Cryptococcosis
• B45.0 Pulmonary cryptococcosis
• B45.1 Cerebral cryptococcosis (this code)
• B45.2 Cutaneous cryptococcosis
• B45.3 Osseous cryptococcosis
• B45.7 Disseminated cryptococcosis
• B45.8 Other forms of cryptococcosis
• B45.9 Cryptococcosis, unspecified