C16.4 Malignant neoplasm of pylorus

Billable ICD-10-CM code, FY2026. Acts as a Complication or Comorbidity (CC) as a secondary diagnosis.

Applicable to

• Malignant neoplasm of prepylorus
• Malignant neoplasm of pyloric canal

Applies from C16 Malignant neoplasm of stomach

Excludes2 (not included here)

• malignant carcinoid tumor of the stomach (C7A.092)

Use additional code

• code to identify:
• alcohol abuse and dependence (F10.-)

Risk adjustment (HCC)

• CMS-HCC V28: HCC 20 — Lung and Other Severe Cancers
• CMS-HCC V22: HCC 9 — Lung and Other Severe Cancers
• RxHCC V08: HCC 22 — Prostate, Breast, Bladder, and Other Cancers and Tumors
• ESRD V24: HCC 9

MS-DRG index

Defines the logic of DRG(s) 374-376 in MDC 06.

Approximate ICD-9-CM (GEMs)

• 151.1 Malignant neoplasm of pylorus

Nearby codes

• C16 Malignant neoplasm of stomach
• C16.0 Malignant neoplasm of cardia
• C16.1 Malignant neoplasm of fundus of stomach
• C16.2 Malignant neoplasm of body of stomach
• C16.3 Malignant neoplasm of pyloric antrum
• C16.4 Malignant neoplasm of pylorus (this code)
• C16.5 Malignant neoplasm of lesser curvature of stomach, unspecified
• C16.6 Malignant neoplasm of greater curvature of stomach, unspecified
• C16.8 Malignant neoplasm of overlapping sites of stomach
• C16.9 Malignant neoplasm of stomach, unspecified