C48.0 Malignant neoplasm of retroperitoneum

Billable ICD-10-CM code, FY2026. Acts as a Complication or Comorbidity (CC) as a secondary diagnosis.

Applies from C48 Malignant neoplasm of retroperitoneum and peritoneum

Excludes1 (never code together)

• Kaposi's sarcoma of connective tissue (C46.1)
• mesothelioma (C45.-)

Risk adjustment (HCC)

• CMS-HCC V28: HCC 20 — Lung and Other Severe Cancers
• CMS-HCC V22: HCC 9 — Lung and Other Severe Cancers
• RxHCC V08: HCC 22 — Prostate, Breast, Bladder, and Other Cancers and Tumors
• ESRD V24: HCC 9

MS-DRG index

Defines the logic of DRG(s) 826-828 in MDC 17.

Approximate ICD-9-CM (GEMs)

• 158.0 Malignant neoplasm of retroperitoneum

Code annotations containing back-references to C48.0

Back-references to C48.0

• Type 2 Excludes: C49 Malignant neoplasm of other connective and soft tissue ("malignant neoplasm of retroperitoneum (C48.0)")

Back-references to C48

• Type 1 Excludes: C26 Malignant neoplasm of other and ill-defined digestive organs ("malignant neoplasm of peritoneum and retroperitoneum (C48.-)")
• Type 1 Excludes: C45.1 Mesothelioma of peritoneum ("other malignant neoplasm of soft tissue of peritoneum (C48.-)")

Nearby codes

• C48 Malignant neoplasm of retroperitoneum and peritoneum
• C48.0 Malignant neoplasm of retroperitoneum (this code)
• C48.1 Malignant neoplasm of specified parts of peritoneum
• C48.2 Malignant neoplasm of peritoneum, unspecified
• C48.8 Malignant neoplasm of overlapping sites of retroperitoneum and peritoneum