C72.9 Malignant neoplasm of central nervous system, unspecified

Billable ICD-10-CM code, FY2026. Acts as a Complication or Comorbidity (CC) as a secondary diagnosis.

Applicable to

• Malignant neoplasm of unspecified site of central nervous system
• Malignant neoplasm of nervous system NOS

Applies from C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system

Excludes1 (never code together)

• malignant neoplasm of meninges (C70.-)
• malignant neoplasm of peripheral nerves and autonomic nervous system (C47.-)

Risk adjustment (HCC)

• CMS-HCC V28: HCC 20 — Lung and Other Severe Cancers
• CMS-HCC V22: HCC 10 — Lymphoma and Other Cancers
• RxHCC V08: HCC 22 — Prostate, Breast, Bladder, and Other Cancers and Tumors
• ESRD V24: HCC 10

MS-DRG index

Defines the logic of DRG(s) 054-055 in MDC 01.

Approximate ICD-9-CM (GEMs)

• 192.8 Malignant neoplasm of other specified sites of nervous system (approximate)
• 192.9 Malignant neoplasm of nervous system, part unspecified (approximate)

Nearby codes

• C72.41 Malignant neoplasm of right acoustic nerve
• C72.42 Malignant neoplasm of left acoustic nerve
• C72.5 Malignant neoplasm of other and unspecified cranial nerves
• C72.50 Malignant neoplasm of unspecified cranial nerve
• C72.59 Malignant neoplasm of other cranial nerves
• C72.9 Malignant neoplasm of central nervous system, unspecified (this code)