D51.0 Vitamin B12 deficiency anemia due to intrinsic factor deficiency

Billable ICD-10-CM code, FY2026.

Applicable to

• Addison anemia
• Biermer anemia
• Pernicious (congenital) anemia
• Congenital intrinsic factor deficiency

Applies from D51 Vitamin B12 deficiency anemia

Excludes1 (never code together)

• vitamin B12 deficiency (E53.8)

MS-DRG index

Defines the logic of DRG(s) 811-812 in MDC 16.

Approximate ICD-9-CM (GEMs)

• 281.0 Pernicious anemia (approximate)

Code annotations containing back-references to D51.0

Back-references to D51.0

• Code First: G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere ("vitamin B12 deficiency anemia due to intrinsic factor deficiency (D51.0)")

Back-references to D51

• Type 1 Excludes: E53.8 Deficiency of other specified B group vitamins ("vitamin B12 deficiency anemia (D51.-)")
• Code First: M90.5 Osteonecrosis in diseases classified elsewhere ("hemoglobinopathy (D50-D64)")
• Type 1 Excludes: R71 Abnormality of red blood cells ("anemias (D50-D64)")

Diagnosis Index entries for D51.0

• Addison's › anemia (pernicious)
• Addison-Biermer anemia (pernicious)
• Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › Addison (-Biermer) (pernicious)
• Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › Biermer's (pernicious)
• Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › combined system disease NEC
• Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › congenital › pernicious
• Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › cytogenic
• Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › deficiency › vitamin B12 NOS › due to › intrinsic factor deficiency
• Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › deficiency › vitamin B12 NOS › pernicious
• Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › malignant (progressive)
• Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › pernicious (congenital) (malignant) (progressive)
• Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › progressive › malignant
• Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › progressive › pernicious
• Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › vitamin › B12 deficiency (dietary) pernicious
• Biermer's (pernicious) anemia or disease
• Congenital › intrinsic factor deficiency
• Deficiency, deficient › intrinsic › factor (congenital)
• Degeneration, degenerative › combined (spinal cord) (subacute) › with anemia (pernicious)
• Disease, diseased › Addison's anemia (pernicious)
• Disease, diseased › Biermer's (pernicious anemia)
• Disease, diseased › Lichtheim's (subacute combined sclerosis with pernicious anemia)
• Disease, diseased › Putnam's (subacute combined sclerosis with pernicious anemia)
• Disease, diseased › Runeberg's (progressive pernicious anemia)
• Glossitis (chronic superficial) (gangrenous) (Moeller's) › Hunter's
• Hunter's › glossitis
• Lichtheim's disease or syndrome
• Myasthenia › syndrome › in › pernicious anemia
• Myelopathy (spinal cord) › in (due to) › pernicious anemia
• Neuropathy, neuropathic › vitamin B12 › with anemia (pernicious)
• Polyneuropathy (peripheral) › in (due to) › vitamin B12 deficiency › with anemia (pernicious)
• Runeberg's disease
• Syndrome › Dana-Putnam
• Syndrome › hunterian glossitis
• Syndrome › Lichtheim's
• Syndrome › Putnam-Dana

Nearby codes

• D51 Vitamin B12 deficiency anemia
• D51.0 Vitamin B12 deficiency anemia due to intrinsic factor deficiency (this code)
• D51.1 Vitamin B12 deficiency anemia due to selective vitamin B12 malabsorption with proteinuria
• D51.2 Transcobalamin II deficiency
• D51.3 Other dietary vitamin B12 deficiency anemia
• D51.8 Other vitamin B12 deficiency anemias
• D51.9 Vitamin B12 deficiency anemia, unspecified