D73.1 Hypersplenism

Billable ICD-10-CM code, FY2026.

Excludes1 (never code together)

• neutropenic splenomegaly (D73.81)
• primary splenic neutropenia (D73.81)
• splenitis, splenomegaly in late syphilis (A52.79)
• splenitis, splenomegaly in tuberculosis (A18.85)
• splenomegaly NOS (R16.1)
• splenomegaly congenital (Q89.0)

MS-DRG index

Defines the logic of DRG(s) 814-816 in MDC 16.

Approximate ICD-9-CM (GEMs)

• 289.4 Hypersplenism

Diagnosis Index entries for D73.1

• Aleukia › splenica
• Big spleen syndrome
• Gamna's disease (siderotic splenomegaly)
• Gandy-Nanta disease (siderotic splenomegaly)
• Hypersplenia, hypersplenism
• Increase, increased › splenic activity
• Metaplasia › myelogenous
• Metaplasia › myeloid (agnogenic) (megakaryocytic)
• Metaplasia › spleen
• Panhematopenia › splenic, primary
• Syndrome › big spleen
• Syndrome › hypersplenic

Nearby codes

• D73 Diseases of spleen
• D73.0 Hyposplenism
• D73.1 Hypersplenism (this code)
• D73.2 Chronic congestive splenomegaly
• D73.3 Abscess of spleen
• D73.4 Cyst of spleen
• D73.5 Infarction of spleen
• D73.8 Other diseases of spleen