E04.1 Nontoxic single thyroid nodule

Billable ICD-10-CM code, FY2026.

Applicable to

• Colloid nodule (cystic) (thyroid)
• Nontoxic uninodular goiter
• Thyroid (cystic) nodule NOS

Applies from E04 Other nontoxic goiter

Excludes1 (never code together)

• congenital goiter (NOS) (diffuse) (parenchymatous) (E03.0)
• iodine-deficiency related goiter (E00-E02)

Risk adjustment (HCC)

• RxHCC V08: HCC 44 — Thyroid Disorders

MS-DRG index

Defines the logic of DRG(s) 011-013 in MDC PRE.

Approximate ICD-9-CM (GEMs)

• 241.0 Nontoxic uninodular goiter (approximate)
• 246.2 Cyst of thyroid (approximate)

Code annotations containing back-references to E04.1

Back-references to E04

• Code First: G63 Polyneuropathy in diseases classified elsewhere ("endocrine disease, except diabetes (E00-E07, E15-E16, E20-E34)")

Diagnosis Index entries for E04.1

• Colloid nodule (of thyroid) (cystic)
• Cyst (colloid) (mucous) (simple) (retention) › thyroid (gland)
• Goiter (plunging) (substernal) › nontoxic › uninodular
• Goiter (plunging) (substernal) › uninodular (nontoxic)
• Nodule (s), nodular › colloid (cystic), thyroid
• Nodule (s), nodular › thyroid (cold) (gland) (nontoxic)
• Struma › nodosa (simplex) › uninodular
• Thyroid (gland) (body) › nodule (cystic) (nontoxic) (single)

Nearby codes

• E04 Other nontoxic goiter
• E04.0 Nontoxic diffuse goiter
• E04.1 Nontoxic single thyroid nodule (this code)
• E04.2 Nontoxic multinodular goiter
• E04.8 Other specified nontoxic goiter
• E04.9 Nontoxic goiter, unspecified