E34.322 Insulin-like growth factor-1 (IGF-1) resistance

Billable ICD-10-CM code, FY2026.

Applicable to

• Genetic syndrome with resistance to insulin-like growth factor-1
• Insulin-like growth factor-1 receptor (IGF-1R) defect
• Post-insulin-like growth factor-1 receptor signaling defect

Applies from E34 Other endocrine disorders

Excludes1 (never code together)

• pseudohypoparathyroidism (E20.1)

Applies from E34.3 Short stature due to endocrine disorder

Excludes1 (never code together)

• achondroplastic short stature (Q77.4)
• hypochondroplastic short stature (Q77.4)
• nutritional short stature (E45)
• pituitary short stature (E23.0)
• progeria (E34.8)
• renal short stature (N25.0)
• Russell-Silver syndrome (Q87.19)
• short-limbed stature with immunodeficiency (D82.2)
• short stature (child) (R62.52)
• short stature in specific dysmorphic syndromes - code to syndrome - see Alphabetical Index
• short stature NOS (R62.52)

MS-DRG index

Defines the logic of DRG(s) 643-645 in MDC 10.

Code annotations containing back-references to E34.322

Back-references to E34.3

• Type 1 Excludes: E23 Hypofunction and other disorders of the pituitary gland ("short stature due to endocrine disorder (E34.3-)")
• Type 1 Excludes: R62.52 Short stature (child) ("short stature due to endocrine disorder (E34.3-)")

Back-references to E34

• Code First: G63 Polyneuropathy in diseases classified elsewhere ("endocrine disease, except diabetes (E00-E07, E15-E16, E20-E34)")

Diagnosis Index entries for E34.322

• Short, shortening, shortness › stature (child) (hereditary) (idiopathic) NEC › due to › genetic causes › genetic syndrome with resistance to insulin-like growth factor-1
• Short, shortening, shortness › stature (child) (hereditary) (idiopathic) NEC › due to › genetic causes › insulin-like growth factor-1 receptor (IGF-1R) defect
• Short, shortening, shortness › stature (child) (hereditary) (idiopathic) NEC › due to › genetic causes › insulin-like growth factor-1 (IGF-1) resistance
• Short, shortening, shortness › stature (child) (hereditary) (idiopathic) NEC › due to › genetic causes › post-insulin-like growth factor-1 receptor signaling defect

Nearby codes

• E34.3 Short stature due to endocrine disorder
• E34.30 Short stature due to endocrine disorder, unspecified
• E34.31 Constitutional short stature
• E34.32 Genetic causes of short stature
• E34.321 Primary insulin-like growth factor-1 (IGF-1) deficiency
• E34.322 Insulin-like growth factor-1 (IGF-1) resistance (this code)
• E34.328 Other genetic causes of short stature
• E34.329 Unspecified genetic causes of short stature
• E34.39 Other short stature due to endocrine disorder
• E34.4 Constitutional tall stature
• E34.5 Androgen insensitivity syndrome