E53.0 Riboflavin deficiency

Billable ICD-10-CM code, FY2026. Acts as a Complication or Comorbidity (CC) as a secondary diagnosis.

Applicable to

• Ariboflavinosis
• Vitamin B2 deficiency

Applies from E53 Deficiency of other B group vitamins

Excludes1 (never code together)

• sequelae of vitamin B deficiency (E64.8)

MS-DRG index

Defines the logic of DRG(s) 640-641 in MDC 10.

Approximate ICD-9-CM (GEMs)

• 266.0 Ariboflavinosis

Code annotations containing back-references to E53.0

Back-references to E53.0

• Type 1 Excludes: K13.0 Diseases of lips ("ariboflavinosis (E53.0)")
• Type 1 Excludes: K13.0 Diseases of lips ("Perlèche due to riboflavin deficiency (E53.0)")

Back-references to E53

• Code First: F06.7 Mild neurocognitive disorder due to known physiological condition ("vitamin B deficiency (E53.-)")
• Code First: G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere ("cerebral degeneration (due to) vitamin B deficiency, except thiamine (E52-E53.-)")
• Code First: G63 Polyneuropathy in diseases classified elsewhere ("nutritional deficiency (E40-E64)")
• Type 1 Excludes: T45.2X6 Underdosing of vitamins ("vitamin deficiencies (E50-E56)")
• Type 1 Excludes: Z72.4 Inappropriate diet and eating habits ("malnutrition and other nutritional deficiencies (E40-E64)")

Diagnosis Index entries for E53.0

• Ariboflavinosis
• Avitaminosis (multiple) › B2
• Avitaminosis (multiple) › G
• Cheilosis (angular) › due to › vitamin B2 (riboflavin) deficiency
• Deficiency, deficient › riboflavin (vitamin B2)
• Deficiency, deficient › vitamin (multiple) NOS › B2 (riboflavin)
• Deficiency, deficient › vitamin (multiple) NOS › G
• Gopalan's syndrome (burning feet)
• Perlèche NEC › due to › riboflavin deficiency
• Perlèche NEC › due to › vitamin B2 (riboflavin) deficiency
• Riboflavin deficiency
• Stomatitis (denture) (ulcerative) › angular › due to dietary or vitamin deficiency
• Stomatitis (denture) (ulcerative) › due to › dietary deficiency
• Stomatitis (denture) (ulcerative) › due to › vitamin deficiency › B2 (riboflavin)

Nearby codes

• E53 Deficiency of other B group vitamins
• E53.0 Riboflavin deficiency (this code)
• E53.1 Pyridoxine deficiency
• E53.8 Deficiency of other specified B group vitamins
• E53.9 Vitamin B deficiency, unspecified