E89.3 Postprocedural hypopituitarism

Billable ICD-10-CM code, FY2026.

Applicable to

• Postirradiation hypopituitarism

Applies from E89 Postprocedural endocrine and metabolic complications and disorders, not elsewhere classified

Excludes2 (not included here)

• intraoperative complications of endocrine system organ or structure (E36.0-, E36.1-, E36.8)

Risk adjustment (HCC)

• CMS-HCC V22: HCC 23 — Other Significant Endocrine and Metabolic Disorders
• RxHCC V08: HCC 43 — Pituitary, Adrenal Gland, and Other Endocrine and Metabolic Disorders
• ESRD V24: HCC 23

MS-DRG index

Defines the logic of DRG(s) 643-645 in MDC 10.

Approximate ICD-9-CM (GEMs)

• 253.7 Iatrogenic pituitary disorders (approximate)

Code annotations containing back-references to E89.3

Back-references to E89.3

• Type 1 Excludes: E23 Hypofunction and other disorders of the pituitary gland ("postprocedural hypopituitarism (E89.3)")

Back-references to E89

• Type 2 Excludes: E36 Intraoperative complications of endocrine system ("postprocedural endocrine and metabolic complications and disorders, not elsewhere classified (E89.-)")
• Type 2 Excludes: T81 Complications of procedures, not elsewhere classified ("intraoperative and postprocedural complications of specific body system (D78.-, E36.-, E89.-, G97.3-, G97.4, H59.3-, H59.-, H95.2-, H95.3, I97.4-, I97.5, J95, K91.-, L76.-, M96.-, N99.-)")
• Type 2 Excludes: Z90 Acquired absence of organs, not elsewhere classified ("postprocedural absence of endocrine glands (E89.-)")

Diagnosis Index entries for E89.3

• Absence (of) (organ or part) (complete or partial) › pituitary gland (congenital) › acquired
• Complication (s) (from) (of) › endocrine › postprocedural › hypopituitarism
• Complication (s) (from) (of) › surgical procedure (on) › hypopituitarism (posthypophysectomy)
• Disorder (of) › pituitary gland › iatrogenic (postprocedural)
• Hypopituitarism (juvenile) › due to › hypophysectomy
• Hypopituitarism (juvenile) › due to › radiotherapy
• Hypopituitarism (juvenile) › postirradiation
• Hypopituitarism (juvenile) › postprocedural

Nearby codes

• E89 Postprocedural endocrine and metabolic complications and disorders, not elsewhere classified
• E89.0 Postprocedural hypothyroidism
• E89.1 Postprocedural hypoinsulinemia
• E89.2 Postprocedural hypoparathyroidism
• E89.3 Postprocedural hypopituitarism (this code)
• E89.4 Postprocedural ovarian failure
• E89.40 Asymptomatic postprocedural ovarian failure
• E89.41 Symptomatic postprocedural ovarian failure
• E89.5 Postprocedural testicular hypofunction
• E89.6 Postprocedural adrenocortical (-medullary) hypofunction