F14.21 Cocaine dependence, in remission

Billable ICD-10-CM code, FY2026.

Applicable to

• Cocaine use disorder, moderate, in early remission
• Cocaine use disorder, moderate, in sustained remission
• Cocaine use disorder, severe, in early remission
• Cocaine use disorder, severe, in sustained remission

Applies from F14 Cocaine related disorders

Excludes2 (not included here)

• other stimulant-related disorders (F15.-)

Applies from F14.2 Cocaine dependence

Excludes1 (never code together)

• cocaine abuse (F14.1-)
• cocaine use, unspecified (F14.9-)

Excludes2 (not included here)

• cocaine poisoning (T40.5-)

Risk adjustment (HCC)

• CMS-HCC V28: HCC 137 — Drug Use Disorder, Moderate/Severe, or Drug Use with Non-Psychotic Complications
• CMS-HCC V22: HCC 55 — Drug/Alcohol Dependence
• ESRD V24: HCC 55

MS-DRG index

Defines the logic of DRG(s) 894-897 in MDC 20.

Approximate ICD-9-CM (GEMs)

• 304.23 Cocaine dependence, in remission

Code annotations containing back-references to F14.21

Back-references to F14.2

• Type 1 Excludes: F14.1 Cocaine abuse ("cocaine dependence (F14.2-)")
• Type 1 Excludes: F14.9 Cocaine use, unspecified ("cocaine dependence (F14.2-)")

Back-references to F14

• Type 2 Excludes: F02 Dementia in other diseases classified elsewhere ("dementia in alcohol and psychoactive substance disorders (F10-F19, with .17, .27, .97)")
• Type 2 Excludes: F06 Other mental disorders due to known physiological condition ("other mental disorders associated with alcohol and other psychoactive substances (F10-F19)")
• Type 2 Excludes: F06.0 Psychotic disorder with hallucinations due to known physiological condition ("hallucinations and perceptual disturbance induced by alcohol and other psychoactive substances (F10-F19 with .151, .251, .951)")
• Type 2 Excludes: F06.2 Psychotic disorder with delusions due to known physiological condition ("alcohol and drug-induced psychotic disorder (F10-F19 with .150, .250, .950)")
• Type 2 Excludes: F06.3 Mood disorder due to known physiological condition ("mood disorders due to alcohol and other psychoactive substances (F10-F19 with .14, .24, .94)")
• Type 2 Excludes: F06.4 Anxiety disorder due to known physiological condition ("anxiety disorders due to alcohol and other psychoactive substances (F10-F19 with .180, .280, .980)")
• Type 2 Excludes: F15 Other stimulant related disorders ("cocaine-related disorders (F14.-)")
• Type 2 Excludes: F20 Schizophrenia ("psychoactive drug use (F11-F19 with .15. .25, .95)")
• Type 2 Excludes: F55 Abuse of non-psychoactive substances ("abuse of psychoactive substances (F10-F19)")
• Type 2 Excludes: F63 Impulse disorders ("habitual excessive use of alcohol or psychoactive substances (F10-F19)")
• Type 2 Excludes: F63.1 Pyromania ("alcohol or psychoactive substance intoxication (F10-F19)")
• Use Additional: O99.32 Drug use complicating pregnancy, childbirth, and the puerperium ("code(s) from F11-F16 and F18-F19 to identify manifestations of the drug use")
• Type 1 Excludes: R41.3 Other amnesia ("amnestic syndrome due to psychoactive substance use (F10-F19 with 5th character .6)")
• Type 1 Excludes: R44 Other symptoms and signs involving general sensations and perceptions ("hallucinations in drug psychosis (F11-F19 with fifth to sixth characters 51)")
• Type 2 Excludes: R78 Findings of drugs and other substances, not normally found in blood ("mental or behavioral disorders due to psychoactive substance use (F10-F19)")
• Use Additional: Z71.5 Drug abuse counseling and surveillance ("code for drug abuse or dependence (F11-F16, F18-F19)")
• Type 2 Excludes: Z79 Long term (current) drug therapy ("drug abuse and dependence (F11-F19)")

Diagnosis Index entries for F14.21

• Dependence (on) (syndrome) › drug NEC › cocaine › in remission
• Disorder (of) › cocaine use › moderate or severe › in remission (early) (sustained)

Nearby codes

• F14.182 Cocaine abuse with cocaine-induced sleep disorder
• F14.188 Cocaine abuse with other cocaine-induced disorder
• F14.19 Cocaine abuse with unspecified cocaine-induced disorder
• F14.2 Cocaine dependence
• F14.20 Cocaine dependence, uncomplicated
• F14.21 Cocaine dependence, in remission (this code)
• F14.22 Cocaine dependence with intoxication
• F14.220 Cocaine dependence with intoxication, uncomplicated
• F14.221 Cocaine dependence with intoxication delirium
• F14.222 Cocaine dependence with intoxication with perceptual disturbance
• F14.229 Cocaine dependence with intoxication, unspecified