F16.21 Hallucinogen dependence, in remission

Billable ICD-10-CM code, FY2026.

Applicable to

• Other hallucinogen use disorder, moderate, in early remission
• Other hallucinogen use disorder, moderate, in sustained remission
• Other hallucinogen use disorder, severe, in early remission
• Other hallucinogen use disorder, severe, in sustained remission
• Phencyclidine use disorder, moderate, in early remission
• Phencyclidine use disorder, moderate, in sustained remission
• Phencyclidine use disorder, severe, in early remission
• Phencyclidine use disorder, severe, in sustained remission

Applies from F16 Hallucinogen related disorders

Includes

• ecstasy
• PCP
• phencyclidine

Applies from F16.2 Hallucinogen dependence

Excludes1 (never code together)

• hallucinogen abuse (F16.1-)
• hallucinogen use, unspecified (F16.9-)

Risk adjustment (HCC)

• CMS-HCC V28: HCC 137 — Drug Use Disorder, Moderate/Severe, or Drug Use with Non-Psychotic Complications
• CMS-HCC V22: HCC 55 — Drug/Alcohol Dependence
• ESRD V24: HCC 55

MS-DRG index

Defines the logic of DRG(s) 894-897 in MDC 20.

Approximate ICD-9-CM (GEMs)

• 304.53 Hallucinogen dependence, in remission

Code annotations containing back-references to F16.21

Back-references to F16.2

• Type 1 Excludes: F16.1 Hallucinogen abuse ("hallucinogen dependence (F16.2-)")
• Type 1 Excludes: F16.9 Hallucinogen use, unspecified ("hallucinogen dependence (F16.2-)")

Back-references to F16

• Type 2 Excludes: F02 Dementia in other diseases classified elsewhere ("dementia in alcohol and psychoactive substance disorders (F10-F19, with .17, .27, .97)")
• Type 2 Excludes: F06 Other mental disorders due to known physiological condition ("other mental disorders associated with alcohol and other psychoactive substances (F10-F19)")
• Type 2 Excludes: F06.0 Psychotic disorder with hallucinations due to known physiological condition ("hallucinations and perceptual disturbance induced by alcohol and other psychoactive substances (F10-F19 with .151, .251, .951)")
• Type 2 Excludes: F06.2 Psychotic disorder with delusions due to known physiological condition ("alcohol and drug-induced psychotic disorder (F10-F19 with .150, .250, .950)")
• Type 2 Excludes: F06.3 Mood disorder due to known physiological condition ("mood disorders due to alcohol and other psychoactive substances (F10-F19 with .14, .24, .94)")
• Type 2 Excludes: F06.4 Anxiety disorder due to known physiological condition ("anxiety disorders due to alcohol and other psychoactive substances (F10-F19 with .180, .280, .980)")
• Type 2 Excludes: F20 Schizophrenia ("psychoactive drug use (F11-F19 with .15. .25, .95)")
• Type 2 Excludes: F55 Abuse of non-psychoactive substances ("abuse of psychoactive substances (F10-F19)")
• Type 2 Excludes: F63 Impulse disorders ("habitual excessive use of alcohol or psychoactive substances (F10-F19)")
• Type 2 Excludes: F63.1 Pyromania ("alcohol or psychoactive substance intoxication (F10-F19)")
• Use Additional: O99.32 Drug use complicating pregnancy, childbirth, and the puerperium ("code(s) from F11-F16 and F18-F19 to identify manifestations of the drug use")
• Type 1 Excludes: R41.3 Other amnesia ("amnestic syndrome due to psychoactive substance use (F10-F19 with 5th character .6)")
• Type 1 Excludes: R44 Other symptoms and signs involving general sensations and perceptions ("hallucinations in drug psychosis (F11-F19 with fifth to sixth characters 51)")
• Type 2 Excludes: R78 Findings of drugs and other substances, not normally found in blood ("mental or behavioral disorders due to psychoactive substance use (F10-F19)")
• Use Additional: Z71.5 Drug abuse counseling and surveillance ("code for drug abuse or dependence (F11-F16, F18-F19)")
• Type 2 Excludes: Z79 Long term (current) drug therapy ("drug abuse and dependence (F11-F19)")

Diagnosis Index entries for F16.21

• Dependence (on) (syndrome) › drug NEC › hallucinogen › in remission
• Disorder (of) › hallucinogen use › moderate or severe › in remission (early) (sustained)
• Disorder (of) › phencyclidine use › moderate or severe › in remission (early) (sustained)

Nearby codes

• F16.183 Hallucinogen abuse with hallucinogen persisting perception disorder (flashbacks)
• F16.188 Hallucinogen abuse with other hallucinogen-induced disorder
• F16.19 Hallucinogen abuse with unspecified hallucinogen-induced disorder
• F16.2 Hallucinogen dependence
• F16.20 Hallucinogen dependence, uncomplicated
• F16.21 Hallucinogen dependence, in remission (this code)
• F16.22 Hallucinogen dependence with intoxication
• F16.220 Hallucinogen dependence with intoxication, uncomplicated
• F16.221 Hallucinogen dependence with intoxication with delirium
• F16.229 Hallucinogen dependence with intoxication, unspecified
• F16.24 Hallucinogen dependence with hallucinogen-induced mood disorder