F19.222 Other psychoactive substance dependence with intoxication with perceptual disturbance

Billable ICD-10-CM code, FY2026. Acts as a Complication or Comorbidity (CC) as a secondary diagnosis.

Applies from F19 Other psychoactive substance related disorders

Includes

• polysubstance drug use (indiscriminate drug use)

Applies from F19.2 Other psychoactive substance dependence

Excludes1 (never code together)

• other psychoactive substance abuse (F19.1-)
• other psychoactive substance use, unspecified (F19.9-)

Applies from F19.22 Other psychoactive substance dependence with intoxication

Excludes1 (never code together)

• other psychoactive substance dependence with withdrawal (F19.23-)

Risk adjustment (HCC)

• CMS-HCC V28: HCC 137 — Drug Use Disorder, Moderate/Severe, or Drug Use with Non-Psychotic Complications
• CMS-HCC V22: HCC 55 — Drug/Alcohol Dependence
• ESRD V24: HCC 55

MS-DRG index

Defines the logic of DRG(s) 894-897 in MDC 20.

Approximate ICD-9-CM (GEMs)

• 292.89 Other specified drug-induced mental disorders (approximate)
• 304.60 Other specified drug dependence, unspecified (approximate)

Code annotations containing back-references to F19.222

Back-references to F19.22

• Type 1 Excludes: F19.23 Other psychoactive substance dependence with withdrawal ("other psychoactive substance dependence with intoxication (F19.22-)")

Back-references to F19.2

• Type 1 Excludes: F19.1 Other psychoactive substance abuse ("other psychoactive substance dependence (F19.2-)")
• Type 1 Excludes: F19.9 Other psychoactive substance use, unspecified ("other psychoactive substance dependence (F19.2-)")

Back-references to F19

• Type 2 Excludes: F02 Dementia in other diseases classified elsewhere ("dementia in alcohol and psychoactive substance disorders (F10-F19, with .17, .27, .97)")
• Type 2 Excludes: F06 Other mental disorders due to known physiological condition ("other mental disorders associated with alcohol and other psychoactive substances (F10-F19)")
• Type 2 Excludes: F06.0 Psychotic disorder with hallucinations due to known physiological condition ("hallucinations and perceptual disturbance induced by alcohol and other psychoactive substances (F10-F19 with .151, .251, .951)")
• Type 2 Excludes: F06.2 Psychotic disorder with delusions due to known physiological condition ("alcohol and drug-induced psychotic disorder (F10-F19 with .150, .250, .950)")
• Type 2 Excludes: F06.3 Mood disorder due to known physiological condition ("mood disorders due to alcohol and other psychoactive substances (F10-F19 with .14, .24, .94)")
• Type 2 Excludes: F06.4 Anxiety disorder due to known physiological condition ("anxiety disorders due to alcohol and other psychoactive substances (F10-F19 with .180, .280, .980)")
• Type 2 Excludes: F20 Schizophrenia ("psychoactive drug use (F11-F19 with .15. .25, .95)")
• Type 2 Excludes: F44.0 Dissociative amnesia ("alcohol-or other psychoactive substance-induced amnestic disorder (F10, F13, F19 with .26, .96)")
• Type 2 Excludes: F55 Abuse of non-psychoactive substances ("abuse of psychoactive substances (F10-F19)")
• Type 2 Excludes: F63 Impulse disorders ("habitual excessive use of alcohol or psychoactive substances (F10-F19)")
• Type 2 Excludes: F63.1 Pyromania ("alcohol or psychoactive substance intoxication (F10-F19)")
• Use Additional: O99.32 Drug use complicating pregnancy, childbirth, and the puerperium ("code(s) from F11-F16 and F18-F19 to identify manifestations of the drug use")
• Type 1 Excludes: R41.3 Other amnesia ("amnestic syndrome due to psychoactive substance use (F10-F19 with 5th character .6)")
• Type 1 Excludes: R44 Other symptoms and signs involving general sensations and perceptions ("hallucinations in drug psychosis (F11-F19 with fifth to sixth characters 51)")
• Type 2 Excludes: R78 Findings of drugs and other substances, not normally found in blood ("mental or behavioral disorders due to psychoactive substance use (F10-F19)")
• Type 2 Excludes: T40 Poisoning by, adverse effect of and underdosing of narcotics and psychodysleptics [hallucinogens] ("drug dependence and related mental and behavioral disorders due to psychoactive substance use (F10.-F19.-)")
• Type 2 Excludes: T42 Poisoning by, adverse effect of and underdosing of antiepileptic, sedative- hypnotic and antiparkinsonism drugs ("drug dependence and related mental and behavioral disorders due to psychoactive substance use (F10.--F19.-)")
• Type 2 Excludes: T43 Poisoning by, adverse effect of and underdosing of psychotropic drugs, not elsewhere classified ("drug dependence and related mental and behavioral disorders due to psychoactive substance use (F10.- -F19.-)")
• Use Additional: Z71.5 Drug abuse counseling and surveillance ("code for drug abuse or dependence (F11-F16, F18-F19)")
• Type 2 Excludes: Z79 Long term (current) drug therapy ("drug abuse and dependence (F11-F19)")

Diagnosis Index entries for F19.222

• Dependence (on) (syndrome) › drug NEC › psychoactive NEC › with › intoxication › with › perceptual disturbance

Nearby codes

• F19.20 Other psychoactive substance dependence, uncomplicated
• F19.21 Other psychoactive substance dependence, in remission
• F19.22 Other psychoactive substance dependence with intoxication
• F19.220 Other psychoactive substance dependence with intoxication, uncomplicated
• F19.221 Other psychoactive substance dependence with intoxication delirium
• F19.222 Other psychoactive substance dependence with intoxication with perceptual disturbance (this code)
• F19.229 Other psychoactive substance dependence with intoxication, unspecified
• F19.23 Other psychoactive substance dependence with withdrawal
• F19.230 Other psychoactive substance dependence with withdrawal, uncomplicated
• F19.231 Other psychoactive substance dependence with withdrawal delirium
• F19.232 Other psychoactive substance dependence with withdrawal with perceptual disturbance