G90.3 Multi-system degeneration of the autonomic nervous system

Billable ICD-10-CM code, FY2026. Acts as a Complication or Comorbidity (CC) as a secondary diagnosis.

Applicable to

• Neurogenic orthostatic hypotension [Shy-Drager]

Excludes1 (never code together)

• orthostatic hypotension NOS (I95.1)

Applies from G90 Disorders of autonomic nervous system

Excludes1 (never code together)

• dysfunction of the autonomic nervous system due to alcohol (G31.2)

Risk adjustment (HCC)

• CMS-HCC V28: HCC 199 — Parkinson and Other Degenerative Disease of Basal Ganglia
• CMS-HCC V22: HCC 78 — Parkinson's and Huntington's Diseases
• RxHCC V08: HCC 161 — Parkinson Disease
• ESRD V24: HCC 78

MS-DRG index

Defines the logic of DRG(s) 056-057 in MDC 01.

Approximate ICD-9-CM (GEMs)

• 333.0 Other degenerative diseases of the basal ganglia (approximate)

Code annotations containing back-references to G90.3

Back-references to G90.3

• Type 1 Excludes: G21 Secondary parkinsonism ("Shy-Drager syndrome (G90.3)")
• Type 2 Excludes: G23 Other degenerative diseases of basal ganglia ("multi-system degeneration of the autonomic nervous system (G90.3)")
• Type 1 Excludes: I95.1 Orthostatic hypotension ("neurogenic orthostatic hypotension [Shy-Drager] (G90.3)")
• Type 1 Excludes: R03.1 Nonspecific low blood-pressure reading ("neurogenic orthostatic hypotension (G90.3)")
• Type 1 Excludes: R55 Syncope and collapse ("neurogenic orthostatic hypotension (G90.3)")

Diagnosis Index entries for G90.3

• Degeneration, degenerative › multi-system
• Hypotension (arterial) (constitutional) › neurogenic, orthostatic
• Hypotension (arterial) (constitutional) › orthostatic (chronic) › neurogenic
• Parkinsonism (idiopathic) (primary) › with neurogenic orthostatic hypotension (symptomatic)
• Shy-Drager syndrome

Nearby codes

• G90.0 Idiopathic peripheral autonomic neuropathy
• G90.01 Carotid sinus syncope
• G90.09 Other idiopathic peripheral autonomic neuropathy
• G90.1 Familial dysautonomia [Riley-Day]
• G90.2 Horner's syndrome
• G90.3 Multi-system degeneration of the autonomic nervous system (this code)
• G90.4 Autonomic dysreflexia
• G90.5 Complex regional pain syndrome I (CRPS I)
• G90.50 Complex regional pain syndrome I, unspecified
• G90.51 Complex regional pain syndrome I of upper limb
• G90.511 Complex regional pain syndrome I of right upper limb