I70.221 Atherosclerosis of native arteries of extremities with rest pain, right leg

Billable ICD-10-CM code, FY2026.

Applies from I70 Atherosclerosis

Includes

• arteriolosclerosis
• arterial degeneration
• arteriosclerosis
• arteriosclerotic vascular disease
• arteriovascular degeneration
• atheroma
• endarteritis deformans or obliterans
• senile arteritis
• senile endarteritis
• vascular degeneration

Excludes2 (not included here)

• arteriosclerotic cardiovascular disease (I25.1-)
• arteriosclerotic heart disease (I25.1-)
• atheroembolism (I75.-)
• cerebral atherosclerosis (I67.2)
• coronary atherosclerosis (I25.1-)
• mesenteric atherosclerosis (K55.1)
• precerebral atherosclerosis (I67.2)
• primary pulmonary atherosclerosis (I27.0)

Use additional code

• code to identify:
• exposure to environmental tobacco smoke (Z77.22)
• history of tobacco dependence (Z87.891)
• occupational exposure to environmental tobacco smoke (Z57.31)
• tobacco dependence (F17.-)
• tobacco use (Z72.0)

Applies from I70.2 Atherosclerosis of native arteries of the extremities

Applicable to

• Mönckeberg's (medial) sclerosis

Excludes2 (not included here)

• atherosclerosis of bypass graft of extremities (I70.30-I70.79)

Use additional code

• code, if applicable, to identify chronic total occlusion of artery of extremity (I70.92)

Applies from I70.22 Atherosclerosis of native arteries of extremities with rest pain

Includes

• any condition classifiable to I70.21-
• chronic limb-threatening ischemia NOS of native arteries of extremities
• chronic limb-threatening ischemia of native arteries of extremities with rest pain
• critical limb ischemia NOS of native arteries of extremities
• critical limb ischemia of native arteries of extremities with rest pain

Risk adjustment (HCC)

• CMS-HCC V28: HCC 264 — Vascular Disease with Complications
• CMS-HCC V22: HCC 108 — Vascular Disease
• ESRD V24: HCC 108

MS-DRG index

Defines the logic of DRG(s) 299-301 in MDC 05.

Approximate ICD-9-CM (GEMs)

• 440.22 Atherosclerosis of native arteries of the extremities with rest pain (approximate)

Medicare Code Edits (MCE v43.1 (April 2026))

• Adult diagnoses (age 15 through 124): Age conflict edit. These diagnoses are clinically expected only in patients age 15 through 124.

Code annotations containing back-references to I70.221

Back-references to I70.2

• Code First: I70.92 Chronic total occlusion of artery of the extremities ("atherosclerosis of arteries of the extremities (I70.2-, I70.3-, I70.4-, I70.5-, I70.6-, I70.7-)")
• Type 1 Excludes: I73.9 Peripheral vascular disease, unspecified ("atherosclerosis of the extremities (I70.2--I70.7-)")

Back-references to I70

• Type 1 Excludes: I77.6 Arteritis, unspecified ("deformans (I70.-)")
• Type 1 Excludes: I77.6 Arteritis, unspecified ("obliterans (I70.-)")
• Type 1 Excludes: I77.6 Arteritis, unspecified ("senile (I70.-)")

Diagnosis Index entries for I70.221

• Arteriosclerosis, arteriosclerotic (diffuse) (obliterans) (of) (senile) (with calcification) › with › critical limb ischemia › leg › right
• Arteriosclerosis, arteriosclerotic (diffuse) (obliterans) (of) (senile) (with calcification) › with › critical limb ischemia › leg › right › with › rest pain (and intermittent claudication)
• Arteriosclerosis, arteriosclerotic (diffuse) (obliterans) (of) (senile) (with calcification) › extremities (native arteries) › leg › right › with › rest pain (and intermittent claudication)

Nearby codes

• I70.212 Atherosclerosis of native arteries of extremities with intermittent claudication, left leg
• I70.213 Atherosclerosis of native arteries of extremities with intermittent claudication, bilateral legs
• I70.218 Atherosclerosis of native arteries of extremities with intermittent claudication, other extremity
• I70.219 Atherosclerosis of native arteries of extremities with intermittent claudication, unspecified extremity
• I70.22 Atherosclerosis of native arteries of extremities with rest pain
• I70.221 Atherosclerosis of native arteries of extremities with rest pain, right leg (this code)
• I70.222 Atherosclerosis of native arteries of extremities with rest pain, left leg
• I70.223 Atherosclerosis of native arteries of extremities with rest pain, bilateral legs
• I70.228 Atherosclerosis of native arteries of extremities with rest pain, other extremity
• I70.229 Atherosclerosis of native arteries of extremities with rest pain, unspecified extremity
• I70.23 Atherosclerosis of native arteries of right leg with ulceration