I82.459 Acute embolism and thrombosis of unspecified peroneal vein

Billable ICD-10-CM code, FY2026. Acts as a Complication or Comorbidity (CC) as a secondary diagnosis.

Applies from I82 Other venous embolism and thrombosis

Excludes2 (not included here)

• venous embolism and thrombosis (of):
• cerebral (I63.6, I67.6)
• coronary (I21-I25)
• intracranial and intraspinal, septic or NOS (G08)
• intracranial, nonpyogenic (I67.6)
• intraspinal, nonpyogenic (G95.1)
• mesenteric (K55.0-)
• portal (I81)
• pulmonary (I26.-)

Code first

• venous embolism and thrombosis complicating:
• abortion, ectopic or molar pregnancy (O00-O07, O08.7)
• pregnancy, childbirth and the puerperium (O22.-, O87.-)

Risk adjustment (HCC)

• CMS-HCC V28: HCC 267 — Deep Vein Thrombosis and Pulmonary Embolism
• CMS-HCC V22: HCC 108 — Vascular Disease
• RxHCC V08: HCC 215 — Venous Thromboembolism
• ESRD V24: HCC 108

MS-DRG index

Defines the logic of DRG(s) 299-301 in MDC 05.

Medicare Code Edits (MCE v43.1 (April 2026))

• Unspecified code (laterality): Unspecified codes for which a more specific code identifying laterality (right, left, bilateral) exists within the same code family.

Code annotations containing back-references to I82.459

Back-references to I82.4

• Type 1 Excludes: I80 Phlebitis and thrombophlebitis ("venous embolism and thrombosis of lower extremities (I82.4-, I82.5-, I82.81-)")
• Use Additional: O22.3 Deep phlebothrombosis in pregnancy ("code to identify the deep vein thrombosis (I82.4-, I82.5-, I82.62-, I82.72-)")
• Use Additional: O87.1 Deep phlebothrombosis in the puerperium ("code to identify the deep vein thrombosis (I82.4-, I82.5-, I82.62-, I82.72-)")

Nearby codes

• I82.449 Acute embolism and thrombosis of unspecified tibial vein
• I82.45 Acute embolism and thrombosis of peroneal vein
• I82.451 Acute embolism and thrombosis of right peroneal vein
• I82.452 Acute embolism and thrombosis of left peroneal vein
• I82.453 Acute embolism and thrombosis of peroneal vein, bilateral
• I82.459 Acute embolism and thrombosis of unspecified peroneal vein (this code)
• I82.46 Acute embolism and thrombosis of calf muscular vein
• I82.461 Acute embolism and thrombosis of right calf muscular vein
• I82.462 Acute embolism and thrombosis of left calf muscular vein
• I82.463 Acute embolism and thrombosis of calf muscular vein, bilateral
• I82.469 Acute embolism and thrombosis of unspecified calf muscular vein