K13.21 Leukoplakia of oral mucosa, including tongue

Billable ICD-10-CM code, FY2026.

Applicable to

• Leukokeratosis of oral mucosa
• Leukoplakia of gingiva, lips, tongue

Excludes1 (never code together)

• hairy leukoplakia (K13.3)
• leukokeratosis nicotina palati (K13.24)

Applies from K13 Other diseases of lip and oral mucosa

Includes

• epithelial disturbances of tongue

Excludes2 (not included here)

• certain disorders of gingiva and edentulous alveolar ridge (K05-K06)
• cysts of oral region (K09.-)
• diseases of tongue (K14.-)
• stomatitis and related lesions (K12.-)

Use additional code

• code to identify:
• alcohol abuse and dependence (F10.-)
• exposure to environmental tobacco smoke (Z77.22)
• exposure to tobacco smoke in the perinatal period (P96.81)
• history of tobacco dependence (Z87.891)
• occupational exposure to environmental tobacco smoke (Z57.31)
• tobacco dependence (F17.-)
• tobacco use (Z72.0)

Applies from K13.2 Leukoplakia and other disturbances of oral epithelium, including tongue

Excludes1 (never code together)

• carcinoma in situ of oral epithelium (D00.0-)
• hairy leukoplakia (K13.3)

MS-DRG index

Defines the logic of DRG(s) 011-013 in MDC PRE.

Approximate ICD-9-CM (GEMs)

• 528.6 Leukoplakia of oral mucosa, including tongue (approximate)

Code annotations containing back-references to K13.21

Back-references to K13.21

• Type 2 Excludes: K05.5 Other periodontal diseases ("leukoplakia of gingiva (K13.21)")
• Type 2 Excludes: K14 Diseases of tongue ("leukoplakia of tongue (K13.21)")

Diagnosis Index entries for K13.21

• Leukokeratosis › mouth
• Leukokeratosis › oral mucosa
• Leukokeratosis › tongue
• Leukoplakia › buccal
• Leukoplakia › gingiva
• Leukoplakia › lip
• Leukoplakia › mouth
• Leukoplakia › oral epithelium, including tongue (mucosa)
• Leukoplakia › palate
• Leukoplakia › tongue

Nearby codes

• K13 Other diseases of lip and oral mucosa
• K13.0 Diseases of lips
• K13.1 Cheek and lip biting
• K13.2 Leukoplakia and other disturbances of oral epithelium, including tongue
• K13.21 Leukoplakia of oral mucosa, including tongue (this code)
• K13.22 Minimal keratinized residual ridge mucosa
• K13.23 Excessive keratinized residual ridge mucosa
• K13.24 Leukokeratosis nicotina palati
• K13.29 Other disturbances of oral epithelium, including tongue
• K13.3 Hairy leukoplakia