L27.0 Generalized skin eruption due to drugs and medicaments taken internally

Billable ICD-10-CM code, FY2026.

Use additional code

• code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Applies from L27 Dermatitis due to substances taken internally

Excludes1 (never code together)

• allergy NOS (T78.40)

Excludes2 (not included here)

• adverse food reaction, except dermatitis (T78.0-T78.1)
• contact dermatitis (L23-L25)
• drug photoallergic response (L56.1)
• drug phototoxic response (L56.0)
• urticaria (L50.-)

MS-DRG index

Defines the logic of DRG(s) 606-607 in MDC 09.

Approximate ICD-9-CM (GEMs)

• 693.0 Dermatitis due to drugs and medicines taken internally (approximate)

Code annotations containing back-references to L27.0

Back-references to L27.0

• Type 2 Excludes: L23.3 Allergic contact dermatitis due to drugs in contact with skin ("dermatitis due to ingested drugs and medicaments (L27.0-L27.1)")
• Type 2 Excludes: L25.1 Unspecified contact dermatitis due to drugs in contact with skin ("dermatitis due to ingested drugs and medicaments (L27.0-L27.1)")
• Type 2 Excludes: T81 Complications of procedures, not elsewhere classified ("dermatitis due to drugs and medicaments (L23.3, L24.4, L25.1, L27.0-L27.1)")
• Type 2 Excludes: T88 Other complications of surgical and medical care, not elsewhere classified ("dermatitis due to drugs and medicaments (L23.3, L24.4, L25.1, L27.0-L27.1)")

Back-references to L27

• Type 2 Excludes: L23 Allergic contact dermatitis ("dermatitis due to substances taken internally (L27.-)")
• Type 2 Excludes: L24 Irritant contact dermatitis ("dermatitis due to substances taken internally (L27.-)")
• Type 2 Excludes: L25 Unspecified contact dermatitis ("dermatitis due to ingested substances (L27.-)")
• Type 1 Excludes: T78.4 Other and unspecified allergy ("dermatitis (L23-L25, L27.-)")

Diagnosis Index entries for L27.0

• Dermatitis (eczematous) › due to › drugs and medicaments (generalized) (internal use)
• Dermatitis (eczematous) › due to › vaccine or vaccination
• Eruption › drug (generalized) (taken internally)
• Eruption › skin (nonspecific) › due to inoculation/vaccination (generalized)
• Rash (toxic) › drug (internal use)

Nearby codes

• L27 Dermatitis due to substances taken internally
• L27.0 Generalized skin eruption due to drugs and medicaments taken internally (this code)
• L27.1 Localized skin eruption due to drugs and medicaments taken internally
• L27.2 Dermatitis due to ingested food
• L27.8 Dermatitis due to other substances taken internally
• L27.9 Dermatitis due to unspecified substance taken internally