L51.2 Toxic epidermal necrolysis [Lyell]
Billable ICD-10-CM code, FY2026. Acts as a Complication or Comorbidity (CC) as a secondary diagnosis.
Applies from L51 Erythema multiforme
Excludes1 (never code together)
- staphylococcal scalded skin syndrome (L00)
- Ritter's disease (L00)
Use additional code
- code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
- code to identify associated manifestations, such as:
- arthropathy associated with dermatological disorders (M14.8-)
- conjunctival edema (H11.42)
- conjunctivitis (H10.22-)
- corneal scars and opacities (H17.-)
- corneal ulcer (H16.0-)
- edema of eyelid (H02.84-)
- inflammation of eyelid (H01.8-)
- keratoconjunctivitis sicca (H16.22-)
- mechanical lagophthalmos (H02.22-)
- stomatitis (K12.-)
- symblepharon (H11.23-)
- code to identify percentage of skin exfoliation (L49.-)
Risk adjustment (HCC)
- CMS-HCC V22: HCC 162 — Severe Skin Burn or Condition
- ESRD V24: HCC 162
MS-DRG index
Defines the logic of DRG(s) 595-596 in MDC 09.
Approximate ICD-9-CM (GEMs)
695.15 Toxic epidermal necrolysis (approximate)
Code annotations containing back-references to L51.2
Back-references to L51.2
- Type 1 Excludes:
L00 Staphylococcal scalded skin syndrome ("toxic epidermal necrolysis [Lyell] (L51.2)") - Code First:
L49 Exfoliation due to erythematous conditions according to extent of body surface involved ("Toxic epidermal necrolysis (L51.2)")
Back-references to L51
- Code First:
M14.8 Arthropathies in other specified diseases classified elsewhere ("erythema multiforme (L51.-)")
Diagnosis Index entries for L51.2
- Epidermolysis › necroticans combustiformis
- Lyell's syndrome
- Lyell's syndrome › due to drug
- Necrolysis, toxic epidermal
Nearby codes
L51 Erythema multiformeL51.0 Nonbullous erythema multiformeL51.1 Stevens-Johnson syndromeL51.2 Toxic epidermal necrolysis [Lyell] (this code)L51.3 Stevens-Johnson syndrome-toxic epidermal necrolysis overlap syndromeL51.8 Other erythema multiformeL51.9 Erythema multiforme, unspecified