M87.10 Osteonecrosis due to drugs, unspecified bone

Billable ICD-10-CM code, FY2026. Acts as a Complication or Comorbidity (CC) as a secondary diagnosis.

Applies from M87 Osteonecrosis

Includes

• avascular necrosis of bone

Excludes1 (never code together)

• juvenile osteonecrosis (M91-M92)
• osteochondropathies (M90-M93)

Use additional code

• code to identify major osseous defect, if applicable (M89.7-)

Applies from M87.1 Osteonecrosis due to drugs

Use additional code

• code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Risk adjustment (HCC)

• CMS-HCC V22: HCC 39 — Bone/Joint/Muscle Infections/Necrosis
• RxHCC V08: HCC 80 — Aseptic Necrosis of Bone
• ESRD V24: HCC 39

MS-DRG index

Defines the logic of DRG(s) 553-554 in MDC 08.

Approximate ICD-9-CM (GEMs)

• 733.40 Aseptic necrosis of bone, site unspecified (approximate)

Medicare Code Edits (MCE v43.1 (April 2026))

• Unspecified code (laterality): Unspecified codes for which a more specific code identifying laterality (right, left, bilateral) exists within the same code family.

Code annotations containing back-references to M87.10

Back-references to M87

• Code First: M89.7 Major osseous defect ("aseptic necrosis of bone (M87.-)")
• Code First: M89.7 Major osseous defect ("osteonecrosis (M87.-)")

Diagnosis Index entries for M87.10

• Osteonecrosis › secondary NEC › due to › drugs

Nearby codes

• M87.078 Idiopathic aseptic necrosis of left toe(s)
• M87.079 Idiopathic aseptic necrosis of unspecified toe(s)
• M87.08 Idiopathic aseptic necrosis of bone, other site
• M87.09 Idiopathic aseptic necrosis of bone, multiple sites
• M87.1 Osteonecrosis due to drugs
• M87.10 Osteonecrosis due to drugs, unspecified bone (this code)
• M87.11 Osteonecrosis due to drugs, shoulder
• M87.111 Osteonecrosis due to drugs, right shoulder
• M87.112 Osteonecrosis due to drugs, left shoulder
• M87.119 Osteonecrosis due to drugs, unspecified shoulder
• M87.12 Osteonecrosis due to drugs, humerus