M87.121 Osteonecrosis due to drugs, right humerus

Billable ICD-10-CM code, FY2026. Acts as a Complication or Comorbidity (CC) as a secondary diagnosis.

Applies from M87 Osteonecrosis

Includes

• avascular necrosis of bone

Excludes1 (never code together)

• juvenile osteonecrosis (M91-M92)
• osteochondropathies (M90-M93)

Use additional code

• code to identify major osseous defect, if applicable (M89.7-)

Applies from M87.1 Osteonecrosis due to drugs

Use additional code

• code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Risk adjustment (HCC)

• CMS-HCC V22: HCC 39 — Bone/Joint/Muscle Infections/Necrosis
• RxHCC V08: HCC 80 — Aseptic Necrosis of Bone
• ESRD V24: HCC 39

MS-DRG index

Defines the logic of DRG(s) 553-554 in MDC 08.

Approximate ICD-9-CM (GEMs)

• 733.41 Aseptic necrosis of head of humerus (approximate)

Code annotations containing back-references to M87.121

Back-references to M87

• Code First: M89.7 Major osseous defect ("aseptic necrosis of bone (M87.-)")
• Code First: M89.7 Major osseous defect ("osteonecrosis (M87.-)")

Nearby codes

• M87.11 Osteonecrosis due to drugs, shoulder
• M87.111 Osteonecrosis due to drugs, right shoulder
• M87.112 Osteonecrosis due to drugs, left shoulder
• M87.119 Osteonecrosis due to drugs, unspecified shoulder
• M87.12 Osteonecrosis due to drugs, humerus
• M87.121 Osteonecrosis due to drugs, right humerus (this code)
• M87.122 Osteonecrosis due to drugs, left humerus
• M87.129 Osteonecrosis due to drugs, unspecified humerus
• M87.13 Osteonecrosis due to drugs of radius, ulna and carpus
• M87.131 Osteonecrosis due to drugs of right radius
• M87.132 Osteonecrosis due to drugs of left radius