N25.81 Secondary hyperparathyroidism of renal origin

Billable ICD-10-CM code, FY2026. Acts as a Complication or Comorbidity (CC) as a secondary diagnosis.

Excludes1 (never code together)

• secondary hyperparathyroidism, non-renal (E21.1)

Excludes2 (not included here)

• metabolic disorders classifiable to E70-E88

Risk adjustment (HCC)

• CMS-HCC V22: HCC 23 — Other Significant Endocrine and Metabolic Disorders
• RxHCC V08: HCC 43 — Pituitary, Adrenal Gland, and Other Endocrine and Metabolic Disorders
• ESRD V24: HCC 23

MS-DRG index

Defines the logic of DRG(s) 698-700 in MDC 11.

Approximate ICD-9-CM (GEMs)

• 588.81 Secondary hyperparathyroidism (of renal origin)

Code annotations containing back-references to N25.81

Back-references to N25.81

• Type 1 Excludes: E21.1 Secondary hyperparathyroidism, not elsewhere classified ("secondary hyperparathyroidism of renal origin (N25.81)")

Diagnosis Index entries for N25.81

• Hyperparathyroidism › secondary (renal)

Nearby codes

• N25 Disorders resulting from impaired renal tubular function
• N25.0 Renal osteodystrophy
• N25.1 Nephrogenic diabetes insipidus
• N25.8 Other disorders resulting from impaired renal tubular function
• N25.81 Secondary hyperparathyroidism of renal origin (this code)
• N25.89 Other disorders resulting from impaired renal tubular function
• N25.9 Disorder resulting from impaired renal tubular function, unspecified