O45.099 Premature separation of placenta with other coagulation defect, unspecified trimester

Billable ICD-10-CM code, FY2026.

MS-DRG index

Defines the logic of DRG(s) 817-819 in MDC 14.

Approximate ICD-9-CM (GEMs)

• 641.30 Antepartum hemorrhage associated with coagulation defects, unspecified as to episode of care or not applicable (approximate)

Medicare Code Edits (MCE v43.1 (April 2026))

• Maternity diagnoses (age 9 through 64): Age conflict edit. These diagnoses are clinically expected only in patients age 9 through 64.

Code annotations containing back-references to O45.099

Back-references to O45.0

• Type 1 Excludes: D65 Disseminated intravascular coagulation [defibrination syndrome] ("pregnancy, childbirth and the puerperium (O45.0, O46.0, O67.0, O72.3)")
• Type 2 Excludes: D68 Other coagulation defects ("coagulation defects complicating pregnancy, childbirth and the puerperium (O45.0, O46.0, O67.0, O72.3)")

Back-references to O45

• Type 2 Excludes: O43 Placental disorders ("premature separation of placenta [abruptio placentae] (O45.-)")
• Type 1 Excludes: O46 Antepartum hemorrhage, not elsewhere classified ("premature separation of placenta [abruptio placentae] (O45.-)")
• Type 1 Excludes: O67 Labor and delivery complicated by intrapartum hemorrhage, not elsewhere classified ("premature separation of placenta [abruptio placentae] (O45.-)")
• Type 1 Excludes: O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium ("hemorrhage with coagulation defects (O45.-, O46.0-, O67.0, O72.3)")

Nearby codes

• O45.029 Premature separation of placenta with disseminated intravascular coagulation, unspecified trimester
• O45.09 Premature separation of placenta with other coagulation defect
• O45.091 Premature separation of placenta with other coagulation defect, first trimester
• O45.092 Premature separation of placenta with other coagulation defect, second trimester
• O45.093 Premature separation of placenta with other coagulation defect, third trimester
• O45.099 Premature separation of placenta with other coagulation defect, unspecified trimester (this code)
• O45.8 Other premature separation of placenta
• O45.8X Other premature separation of placenta
• O45.8X1 Other premature separation of placenta, first trimester
• O45.8X2 Other premature separation of placenta, second trimester
• O45.8X3 Other premature separation of placenta, third trimester