O45.93 Premature separation of placenta, unspecified, third trimester

Billable ICD-10-CM code, FY2026. Acts as a Major Complication or Comorbidity (MCC) as a secondary diagnosis.

Applies from O45.9 Premature separation of placenta, unspecified

Applicable to

• Abruptio placentae NOS

MS-DRG index

Defines the logic of DRG(s) 817-819 in MDC 14.

Approximate ICD-9-CM (GEMs)

• 641.21 Premature separation of placenta, delivered, with or without mention of antepartum condition (approximate)
• 641.23 Premature separation of placenta, antepartum condition or complication (approximate)

Medicare Code Edits (MCE v43.1 (April 2026))

• Maternity diagnoses (age 9 through 64): Age conflict edit. These diagnoses are clinically expected only in patients age 9 through 64.

Code annotations containing back-references to O45.93

Back-references to O45

• Type 2 Excludes: O43 Placental disorders ("premature separation of placenta [abruptio placentae] (O45.-)")
• Type 1 Excludes: O46 Antepartum hemorrhage, not elsewhere classified ("premature separation of placenta [abruptio placentae] (O45.-)")
• Type 1 Excludes: O67 Labor and delivery complicated by intrapartum hemorrhage, not elsewhere classified ("premature separation of placenta [abruptio placentae] (O45.-)")
• Type 1 Excludes: O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium ("hemorrhage with coagulation defects (O45.-, O46.0-, O67.0, O72.3)")

Nearby codes

• O45.8X9 Other premature separation of placenta, unspecified trimester
• O45.9 Premature separation of placenta, unspecified
• O45.90 Premature separation of placenta, unspecified, unspecified trimester
• O45.91 Premature separation of placenta, unspecified, first trimester
• O45.92 Premature separation of placenta, unspecified, second trimester
• O45.93 Premature separation of placenta, unspecified, third trimester (this code)