O75.3 Other infection during labor

Billable ICD-10-CM code, FY2026. Acts as a Major Complication or Comorbidity (MCC) as a secondary diagnosis.

Applicable to

• Sepsis during labor

Use additional code

• code (B95-B97), to identify infectious agent

Applies from O75 Other complications of labor and delivery, not elsewhere classified

Excludes2 (not included here)

• puerperal (postpartum) infection (O86.-)
• puerperal (postpartum) sepsis (O85)

MS-DRG index

Defines the logic of DRG(s) 817-819 in MDC 14.

Approximate ICD-9-CM (GEMs)

• 659.31 Generalized infection during labor, delivered, with or without mention of antepartum condition (approximate)

Medicare Code Edits (MCE v43.1 (April 2026))

• Maternity diagnoses (age 9 through 64): Age conflict edit. These diagnoses are clinically expected only in patients age 9 through 64.

Code annotations containing back-references to O75.3

Back-references to O75.3

• Code First: A40 Streptococcal sepsis ("streptococcal sepsis during labor (O75.3)")
• Code First: A41 Other sepsis ("sepsis during labor (O75.3)")
• Type 2 Excludes: O85 Puerperal sepsis ("sepsis during labor (O75.3)")
• Type 2 Excludes: O86 Other puerperal infections ("infection during labor (O75.3)")

Diagnosis Index entries for O75.3

• Infection, infected, infective (opportunistic) › during labor NEC
• Sepsis (generalized) (unspecified organism) › during labor

Nearby codes

• O75 Other complications of labor and delivery, not elsewhere classified
• O75.0 Maternal distress during labor and delivery
• O75.1 Shock during or following labor and delivery
• O75.2 Pyrexia during labor, not elsewhere classified
• O75.3 Other infection during labor (this code)
• O75.4 Other complications of obstetric surgery and procedures
• O75.5 Delayed delivery after artificial rupture of membranes
• O75.8 Other specified complications of labor and delivery
• O75.81 Maternal exhaustion complicating labor and delivery
• O75.82 Onset (spontaneous) of labor after 37 completed weeks of gestation but before 39 completed weeks gestation, with delivery by (planned) cesarean section