O88.112 Amniotic fluid embolism in pregnancy, second trimester

Billable ICD-10-CM code, FY2026. Acts as a Major Complication or Comorbidity (MCC) as a secondary diagnosis.

Applies from O88 Obstetric embolism

Excludes1 (never code together)

• embolism complicating abortion NOS (O03.2)
• embolism complicating ectopic or molar pregnancy (O08.2)
• embolism complicating failed attempted abortion (O07.2)
• embolism complicating induced abortion (O04.7)
• embolism complicating spontaneous abortion (O03.2, O03.7)

Applies from O88.1 Amniotic fluid embolism

Applicable to

• Anaphylactoid syndrome in pregnancy

MS-DRG index

Defines the logic of DRG(s) 817-819 in MDC 14.

Approximate ICD-9-CM (GEMs)

• 673.11 Amniotic fluid embolism, delivered, with or without mention of antepartum condition (approximate)
• 673.13 Amniotic fluid embolism, antepartum condition or complication (approximate)

Medicare Code Edits (MCE v43.1 (April 2026))

• Maternity diagnoses (age 9 through 64): Age conflict edit. These diagnoses are clinically expected only in patients age 9 through 64.

Code annotations containing back-references to O88.112

Back-references to O88

• Type 2 Excludes: I26 Pulmonary embolism ("pulmonary embolism complicating pregnancy, childbirth and the puerperium (O88.-)")
• Code First: I74 Arterial embolism and thrombosis ("embolism and thrombosis complicating pregnancy, childbirth and the puerperium (O88.-)")
• Type 2 Excludes: O22 Venous complications and hemorrhoids in pregnancy ("obstetric pulmonary embolism (O88.-)")
• Type 2 Excludes: O87 Venous complications and hemorrhoids in the puerperium ("obstetric embolism (O88.-)")
• Type 2 Excludes: O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium ("obstetric embolism (O88.-)")
• Type 1 Excludes: T81.7 Vascular complications following a procedure, not elsewhere classified ("embolism complicating pregnancy, childbirth and the puerperium (O88.-)")

Nearby codes

• O88.02 Air embolism in childbirth
• O88.03 Air embolism in the puerperium
• O88.1 Amniotic fluid embolism
• O88.11 Amniotic fluid embolism in pregnancy
• O88.111 Amniotic fluid embolism in pregnancy, first trimester
• O88.112 Amniotic fluid embolism in pregnancy, second trimester (this code)
• O88.113 Amniotic fluid embolism in pregnancy, third trimester
• O88.119 Amniotic fluid embolism in pregnancy, unspecified trimester
• O88.12 Amniotic fluid embolism in childbirth
• O88.13 Amniotic fluid embolism in the puerperium
• O88.2 Obstetric thromboembolism