P22.0 Respiratory distress syndrome of newborn

Billable ICD-10-CM code, FY2026. Acts as a Major Complication or Comorbidity (MCC) as a secondary diagnosis.

Applicable to

• Cardiorespiratory distress syndrome of newborn
• Hyaline membrane disease
• Idiopathic respiratory distress syndrome [IRDS or RDS] of newborn
• Pulmonary hypoperfusion syndrome
• Respiratory distress syndrome, type I

Excludes2 (not included here)

• respiratory arrest of newborn (P28.81)
• respiratory failure of newborn NOS (P28.5)

Risk adjustment (HCC)

• CMS-HCC V28: HCC 213 — Cardio-Respiratory Failure and Shock

MS-DRG index

Defines the logic of DRG(s) 790 in MDC 15.

Approximate ICD-9-CM (GEMs)

• 769 Respiratory distress syndrome in newborn

Code annotations containing back-references to P22.0

Back-references to P22.0

• Type 1 Excludes: J80 Acute respiratory distress syndrome ("respiratory distress syndrome in newborn (perinatal) (P22.0)")
• Type 1 Excludes: J96 Respiratory failure, not elsewhere classified ("newborn respiratory distress syndrome (P22.0)")
• Type 2 Excludes: P27 Chronic respiratory disease originating in the perinatal period ("respiratory distress of newborn (P22.0-P22.9)")
• Type 1 Excludes: P28.11 Resorption atelectasis without respiratory distress syndrome ("resorption atelectasis with respiratory distress syndrome (P22.0)")
• Type 2 Excludes: P28.5 Respiratory failure of newborn ("respiratory distress of newborn (P22.0)")
• Type 1 Excludes: R09 Other symptoms and signs involving the circulatory and respiratory system ("respiratory distress syndrome of newborn (P22.0)")
• Type 1 Excludes: R09.2 Respiratory arrest ("respiratory distress of newborn (P22.0)")
• Type 2 Excludes: T79 Certain early complications of trauma, not elsewhere classified ("newborn respiratory distress syndrome (P22.0)")

Back-references to P22

• Type 1 Excludes: R06 Abnormalities of breathing ("respiratory distress syndrome of newborn (P22.-)")
• Type 1 Excludes: T71 Asphyxiation ("respiratory distress (syndrome) in newborn (P22.-)")

Diagnosis Index entries for P22.0

• Disease, diseased › hyaline (diffuse) (generalized) › membrane (lung) (newborn)
• Hyaline membrane (disease) (lung) (pulmonary) (newborn)
• IRDS (type I)
• RDS (newborn) (type I)
• Respiratory › distress syndrome (newborn) (type I)
• Syndrome › cardiorespiratory distress (idiopathic), newborn
• Syndrome › idiopathic › cardiorespiratory distress, newborn
• Syndrome › IRDS (idiopathic respiratory distress, newborn)
• Syndrome › pulmonary › hypoperfusion (idiopathic)
• Syndrome › RDS (respiratory distress syndrome, newborn)
• Syndrome › respiratory › distress › newborn (idiopathic) (type I)

Nearby codes

• P22 Respiratory distress of newborn
• P22.0 Respiratory distress syndrome of newborn (this code)
• P22.1 Transient tachypnea of newborn
• P22.8 Other respiratory distress of newborn
• P22.9 Respiratory distress of newborn, unspecified