P91.3 Neonatal cerebral irritability

Billable ICD-10-CM code, FY2026. Acts as a Major Complication or Comorbidity (MCC) as a secondary diagnosis.

Risk adjustment (HCC)

• CMS-HCC V28: HCC 202 — Coma, Brain Compression/Anoxic Damage

MS-DRG index

Defines the logic of DRG(s) 791 in MDC 15.

Approximate ICD-9-CM (GEMs)

• 779.2 Cerebral depression, coma, and other abnormal cerebral signs in fetus or newborn (approximate)

Code annotations containing back-references to P91.3

Back-references to P91.3

• Type 1 Excludes: P91.6 Hypoxic ischemic encephalopathy [HIE] ("Neonatal cerebral irritability (P91.3)")
• Type 1 Excludes: R68.1 Nonspecific symptoms peculiar to infancy ("neonatal cerebral irritability (P91.3)")

Diagnosis Index entries for P91.3

• Irritable, irritability › cerebral, in newborn

Nearby codes

• P91 Other disturbances of cerebral status of newborn
• P91.0 Neonatal cerebral ischemia
• P91.1 Acquired periventricular cysts of newborn
• P91.2 Neonatal cerebral leukomalacia
• P91.3 Neonatal cerebral irritability (this code)
• P91.4 Neonatal cerebral depression
• P91.5 Neonatal coma
• P91.6 Hypoxic ischemic encephalopathy [HIE]
• P91.60 Hypoxic ischemic encephalopathy [HIE], unspecified
• P91.61 Mild hypoxic ischemic encephalopathy [HIE]