Q98.1 Klinefelter syndrome, male with more than two X chromosomes

Billable ICD-10-CM code, FY2026. Exempt from present-on-admission (POA) reporting.

MS-DRG index

Defines the logic of DRG(s) 729-730 in MDC 12.

Approximate ICD-9-CM (GEMs)

• 758.7 Klinefelter's syndrome (approximate)

Code annotations containing back-references to Q98.1

Back-references to Q98.1

• Type 1 Excludes: E29 Testicular dysfunction ("Klinefelter's syndrome (Q98.0-Q98.1, Q98.4)")

Back-references to Q98

• Code First: D84.81 Immunodeficiency due to conditions classified elsewhere ("chromosomal abnormalities (Q90-Q99)")
• Type 1 Excludes: E25 Adrenogenital disorders ("chromosomal abnormalities (Q90-Q99)")
• Type 1 Excludes: Q56 Indeterminate sex and pseudohermaphroditism ("pseudohermaphroditism with specified chromosomal anomaly (Q96-Q99)")
• Type 1 Excludes: Z15 Genetic susceptibility to disease ("chromosomal anomalies (Q90-Q99)")

Diagnosis Index entries for Q98.1

• Klinefelter's syndrome › male with more than two X chromosomes
• Syndrome › XXXXY
• XXXXY syndrome

Nearby codes

• Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified
• Q98.0 Klinefelter syndrome karyotype 47, XXY
• Q98.1 Klinefelter syndrome, male with more than two X chromosomes (this code)
• Q98.3 Other male with 46, XX karyotype
• Q98.4 Klinefelter syndrome, unspecified
• Q98.5 Karyotype 47, XYY
• Q98.6 Male with structurally abnormal sex chromosome
• Q98.7 Male with sex chromosome mosaicism