R11.16 Cannabis hyperemesis syndrome

Billable ICD-10-CM code, FY2026.

Applicable to

• Cannabinoid hyperemesis syndrome

Code also

• cannabis abuse (F12.1-)
• cannabis dependence (F12.2-)
• cannabis use, unspecified (F12.92-, F12.93, F12.95-, F12.98-, F12.99)
• manifestations, such as:
• dehydration (E86.0)
• electrolyte imbalance (E87.8}

Applies from R11 Nausea and vomiting

Excludes1 (never code together)

• cyclical vomiting associated with migraine (G43.A-)
• excessive vomiting in pregnancy (O21.-)
• hematemesis (K92.0)
• neonatal hematemesis (P54.0)
• newborn vomiting (P92.0-)
• psychogenic vomiting (F50.89)
• vomiting associated with bulimia nervosa (F50.2-)
• vomiting following gastrointestinal surgery (K91.0)

Risk adjustment (HCC)

• CMS-HCC V28: HCC 137 — Drug Use Disorder, Moderate/Severe, or Drug Use with Non-Psychotic Complications
• CMS-HCC V22: HCC 55 — Drug/Alcohol Dependence
• ESRD V24: HCC 55

MS-DRG index

Defines the logic of DRG(s) 391-392 in MDC 06.

Code annotations containing back-references to R11.16

Back-references to R11

• Type 1 Excludes: P92.0 Vomiting of newborn ("vomiting of child over 28 days old (R11.-)")

Diagnosis Index entries for R11.16

• Syndrome › cannabinoid hyperemesis
• Syndrome › cannabis hyperemesis

Nearby codes

• R11.11 Vomiting without nausea
• R11.12 Projectile vomiting
• R11.13 Vomiting of fecal matter
• R11.14 Bilious vomiting
• R11.15 Cyclical vomiting syndrome unrelated to migraine
• R11.16 Cannabis hyperemesis syndrome (this code)
• R11.2 Nausea with vomiting, unspecified