R45.4 Irritability and anger

Billable ICD-10-CM code, FY2026.

MS-DRG index

Defines the logic of DRG(s) 880 in MDC 19.

Approximate ICD-9-CM (GEMs)

• 799.22 Irritability (approximate)

Code annotations containing back-references to R45.4

Back-references to R45

• Type 1 Excludes: F07.0 Personality change due to known physiological condition ("signs and symptoms involving emotional state (R45.-)")

Diagnosis Index entries for R45.4

• Anger
• Irritable, irritability

Nearby codes

• R45 Symptoms and signs involving emotional state
• R45.0 Nervousness
• R45.1 Restlessness and agitation
• R45.2 Unhappiness
• R45.3 Demoralization and apathy
• R45.4 Irritability and anger (this code)
• R45.5 Hostility
• R45.6 Violent behavior
• R45.7 State of emotional shock and stress, unspecified
• R45.8 Other symptoms and signs involving emotional state
• R45.81 Low self-esteem