R50.2 Drug induced fever

Billable ICD-10-CM code, FY2026.

Excludes1 (never code together)

• postvaccination (postimmunization) fever (R50.83)

Use additional code

• code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Applies from R50 Fever of other and unknown origin

Excludes1 (never code together)

• chills without fever (R68.83)
• febrile convulsions (R56.0-)
• fever of unknown origin during labor (O75.2)
• fever of unknown origin in newborn (P81.9)
• hypothermia due to illness (R68.0)
• malignant hyperthermia due to anesthesia (T88.3)
• puerperal pyrexia NOS (O86.4)

MS-DRG index

Defines the logic of DRG(s) 864 in MDC 18.

Approximate ICD-9-CM (GEMs)

• 780.60 Fever, unspecified (approximate)
• E947.9 Unspecified drug or medicinal substance causing adverse effects in therapeutic use (approximate)

Diagnosis Index entries for R50.2

• Drug › induced fever
• Fever (inanition) (of unknown origin) (persistent) (with chills) (with rigor) › drug induced
• Fever (inanition) (of unknown origin) (persistent) (with chills) (with rigor) › iodide
• Fever (inanition) (of unknown origin) (persistent) (with chills) (with rigor) › steroid
• Steroid › effects (adverse) (adrenocortical) (iatrogenic) › fever

Nearby codes

• R50 Fever of other and unknown origin
• R50.2 Drug induced fever (this code)
• R50.8 Other specified fever
• R50.81 Fever presenting with conditions classified elsewhere
• R50.82 Postprocedural fever
• R50.83 Postvaccination fever
• R50.84 Febrile nonhemolytic transfusion reaction