R59.1 Generalized enlarged lymph nodes

Billable ICD-10-CM code, FY2026.

Applicable to

• Lymphadenopathy NOS

Applies from R59 Enlarged lymph nodes

Includes

• swollen glands

Excludes1 (never code together)

• lymphadenitis NOS (I88.9)
• acute lymphadenitis (L04.-)
• chronic lymphadenitis (I88.1)
• mesenteric (acute) (chronic) lymphadenitis (I88.0)

MS-DRG index

Defines the logic of DRG(s) 814-816 in MDC 16.

Approximate ICD-9-CM (GEMs)

• 785.6 Enlargement of lymph nodes (approximate)

Code annotations containing back-references to R59.1

Back-references to R59

• Type 2 Excludes: D75 Other and unspecified diseases of blood and blood-forming organs ("enlarged lymph nodes (R59.-)")
• Type 1 Excludes: I88 Nonspecific lymphadenitis ("enlarged lymph nodes NOS (R59.-)")
• Type 1 Excludes: I89 Other noninfective disorders of lymphatic vessels and lymph nodes ("enlarged lymph nodes NOS (R59.-)")
• Type 1 Excludes: L04 Acute lymphadenitis ("enlarged lymph nodes (R59.-)")
• Type 1 Excludes: R22 Localized swelling, mass and lump of skin and subcutaneous tissue ("enlarged lymph nodes (R59.-)")

Diagnosis Index entries for R59.1

• Adenopathy (lymph gland) › generalized
• Enlargement, enlarged › lymph gland or node › generalized
• Hypertrophy, hypertrophic › gland, glandular › generalized
• Hypertrophy, hypertrophic › lymph, lymphatic gland › generalized
• Lymphadenopathy (generalized)
• Lymphadenosis
• Swelling (of) › glands › generalized

Nearby codes

• R59 Enlarged lymph nodes
• R59.0 Localized enlarged lymph nodes
• R59.1 Generalized enlarged lymph nodes (this code)
• R59.9 Enlarged lymph nodes, unspecified