T80.310A ABO incompatibility with acute hemolytic transfusion reaction, initial encounter

Billable ICD-10-CM code, FY2026.

Built from T80.310 with 7th character A (initial encounter).

Applies from T80 Complications following infusion, transfusion and therapeutic injection

Includes

• complications following perfusion

Excludes2 (not included here)

• bone marrow transplant rejection (T86.01)
• febrile nonhemolytic transfusion reaction (R50.84)
• fluid overload due to transfusion (E87.71)
• posttransfusion purpura (D69.51)
• transfusion associated circulatory overload (TACO) (E87.71)
• transfusion (red blood cell) associated hemochromatosis (E83.111)
• transfusion related acute lung injury (TRALI) (J95.84)

7th character note

• The appropriate 7th character is to be added to each code from category T80

7th character required

• A — initial encounter
• D — subsequent encounter
• S — sequela

Applies from T80.3 ABO incompatibility reaction due to transfusion of blood or blood products

Excludes1 (never code together)

• minor blood group antigens reactions (Duffy) (E) (K) (Kell) (Kidd) (Lewis) (M) (N) (P) (S) (T80.A-)

Applies from T80.310 ABO incompatibility with acute hemolytic transfusion reaction

Applicable to

• ABO incompatibility with hemolytic transfusion reaction less than 24 hours after transfusion
• Acute hemolytic transfusion reaction (AHTR) due to ABO incompatibility

Code annotations containing back-references to T80.310A

Back-references to T80.31

• Type 1 Excludes: T80.91 Hemolytic transfusion reaction, unspecified incompatibility ("ABO incompatibility with hemolytic transfusion reaction (T80.31-)")

Back-references to T80.3

• Type 1 Excludes: T80.5 Anaphylactic reaction due to serum ("ABO incompatibility reaction due to transfusion of blood or blood products (T80.3-)")

Back-references to T80

• Type 2 Excludes: T45.8 Poisoning by, adverse effect of and underdosing of other primarily systemic and hematological agents ("transfusion reactions (T80.-)")
• Type 2 Excludes: T78 Adverse effects, not elsewhere classified ("complications of surgical and medical care NEC (T80-T88)")
• Type 2 Excludes: T79 Certain early complications of trauma, not elsewhere classified ("complications occurring during or following medical procedures (T80-T88)")
• Type 2 Excludes: T79 Certain early complications of trauma, not elsewhere classified ("complications of surgical and medical care NEC (T80-T88)")
• Type 2 Excludes: T81 Complications of procedures, not elsewhere classified ("complications following infusion, transfusion and therapeutic injection (T80.-)")
• Type 2 Excludes: T88 Other complications of surgical and medical care, not elsewhere classified ("complication following infusion, transfusion and therapeutic injection (T80.-)")
• Type 1 Excludes: T88.7 Unspecified adverse effect of drug or medicament ("specified adverse effects of drugs and medicaments (A00-R94 and T80-T88.6, T88.8)")

Diagnosis Index entries for T80.310A

• Complication (s) (from) (of) › transfusion (blood) (lymphocytes) (plasma) › incompatibility reaction (antigen unspecified) › ABO › hemolytic transfusion reaction (HTR) (unspecified time after transfusion) › acute (AHTR) (less than 24 hours after transfusion)

Nearby codes

• T80.30XA ABO incompatibility reaction due to transfusion of blood or blood products, unspecified, initial encounter
• T80.30XD ABO incompatibility reaction due to transfusion of blood or blood products, unspecified, subsequent encounter
• T80.30XS ABO incompatibility reaction due to transfusion of blood or blood products, unspecified, sequela
• T80.31 ABO incompatibility with hemolytic transfusion reaction
• T80.310 ABO incompatibility with acute hemolytic transfusion reaction
• T80.310A ABO incompatibility with acute hemolytic transfusion reaction, initial encounter (this code)
• T80.310D ABO incompatibility with acute hemolytic transfusion reaction, subsequent encounter
• T80.310S ABO incompatibility with acute hemolytic transfusion reaction, sequela
• T80.311 ABO incompatibility with delayed hemolytic transfusion reaction
• T80.311A ABO incompatibility with delayed hemolytic transfusion reaction, initial encounter
• T80.311D ABO incompatibility with delayed hemolytic transfusion reaction, subsequent encounter