T80.82 Complication of immune effector cellular therapy

Non-billable ICD-10-CM code.

Applicable to

• Complication of chimeric antigen receptor (CAR-T) cell therapy
• Complication of IEC therapy

Excludes2 (not included here)

• adverse effect of immune checkpoint inhibitors and immunostimulant drugs (T45.AX5)
• complication of bone marrow transplant (T86.0)
• complication of stem cell transplant (T86.5)

Use additional code

• code to identify the specific complication, such as:
• cytokine release syndrome (D89.83-)
• immune effector cell-associated neurotoxicity syndrome (G92.0-)

Applies from T80 Complications following infusion, transfusion and therapeutic injection

Includes

• complications following perfusion

Excludes2 (not included here)

• bone marrow transplant rejection (T86.01)
• febrile nonhemolytic transfusion reaction (R50.84)
• fluid overload due to transfusion (E87.71)
• posttransfusion purpura (D69.51)
• transfusion associated circulatory overload (TACO) (E87.71)
• transfusion (red blood cell) associated hemochromatosis (E83.111)
• transfusion related acute lung injury (TRALI) (J95.84)

7th character note

• The appropriate 7th character is to be added to each code from category T80

7th character required

• A — initial encounter
• D — subsequent encounter
• S — sequela

Code annotations containing back-references to T80.82

Back-references to T80.82

• Code First: G92.0 Immune effector cell-associated neurotoxicity syndrome ("complications of immune effector cellular therapy (T80.82)")

Back-references to T80

• Type 2 Excludes: T45.8 Poisoning by, adverse effect of and underdosing of other primarily systemic and hematological agents ("transfusion reactions (T80.-)")
• Type 2 Excludes: T78 Adverse effects, not elsewhere classified ("complications of surgical and medical care NEC (T80-T88)")
• Type 2 Excludes: T79 Certain early complications of trauma, not elsewhere classified ("complications occurring during or following medical procedures (T80-T88)")
• Type 2 Excludes: T79 Certain early complications of trauma, not elsewhere classified ("complications of surgical and medical care NEC (T80-T88)")
• Type 2 Excludes: T81 Complications of procedures, not elsewhere classified ("complications following infusion, transfusion and therapeutic injection (T80.-)")
• Type 2 Excludes: T88 Other complications of surgical and medical care, not elsewhere classified ("complication following infusion, transfusion and therapeutic injection (T80.-)")
• Type 1 Excludes: T88.7 Unspecified adverse effect of drug or medicament ("specified adverse effects of drugs and medicaments (A00-R94 and T80-T88.6, T88.8)")

Diagnosis Index entries for T80.82

• Complication (s) (from) (of) › chimeric antigen receptor (CAR-T) cell therapy
• Complication (s) (from) (of) › IEC (immune effector cellular) therapy
• Complication (s) (from) (of) › immune effector cellular (IEC) therapy

Nearby codes

• T80.810S Extravasation of vesicant antineoplastic chemotherapy, sequela
• T80.818 Extravasation of other vesicant agent
• T80.818A Extravasation of other vesicant agent, initial encounter
• T80.818D Extravasation of other vesicant agent, subsequent encounter
• T80.818S Extravasation of other vesicant agent, sequela
• T80.82 Complication of immune effector cellular therapy (this code)
• T80.82XA Complication of immune effector cellular therapy, initial encounter
• T80.82XD Complication of immune effector cellular therapy, subsequent encounter
• T80.82XS Complication of immune effector cellular therapy, sequela
• T80.89 Other complications following infusion, transfusion and therapeutic injection
• T80.89XA Other complications following infusion, transfusion and therapeutic injection, initial encounter