Z79.890 Hormone replacement therapy

Billable ICD-10-CM code, FY2026. Exempt from present-on-admission (POA) reporting.

Applies from Z79 Long term (current) drug therapy

Includes

• long term (current) drug use for prophylactic purposes

Excludes2 (not included here)

• drug abuse and dependence (F11-F19)
• drug use complicating pregnancy, childbirth, and the puerperium (O99.32-)

Code also

• any therapeutic drug level monitoring (Z51.81)

MS-DRG index

Defines the logic of DRG(s) 951 in MDC 23.

Approximate ICD-9-CM (GEMs)

• V07.4 Hormone replacement therapy (postmenopausal)

Medicare Code Edits (MCE v43.1 (April 2026))

• Unacceptable principal diagnosis: These codes describe a circumstance which influences care but is not a current illness or injury, or capture only an underlying condition, and are unacceptable as principal diagnosis.

Code annotations containing back-references to Z79.890

Back-references to Z79.890

• Type 1 Excludes: Z79.81 Long term (current) use of agents affecting estrogen receptors and estrogen levels ("hormone replacement therapy (Z79.890)")

Back-references to Z79

• Code Also: Z51.81 Encounter for therapeutic drug level monitoring ("any long-term (current) drug therapy (Z79.-)")
• Type 2 Excludes: Z92.2 Personal history of drug therapy ("long term (current) drug therapy (Z79.-)")

Diagnosis Index entries for Z79.890

• Long-term (current) (prophylactic) drug therapy (use of) › hormone replacement
• Therapy › drug, long-term (current) (prophylactic) › hormone replacement

Nearby codes

• Z79.82 Long term (current) use of aspirin
• Z79.83 Long term (current) use of bisphosphonates
• Z79.84 Long term (current) use of oral hypoglycemic drugs
• Z79.85 Long-term (current) use of injectable non-insulin antidiabetic drugs
• Z79.89 Other long term (current) drug therapy
• Z79.890 Hormone replacement therapy (this code)
• Z79.891 Long term (current) use of opiate analgesic
• Z79.899 Other long term (current) drug therapy