Z80.42 Family history of malignant neoplasm of prostate

Billable ICD-10-CM code, FY2026. Exempt from present-on-admission (POA) reporting.

Applies from Z80.4 Family history of malignant neoplasm of genital organs

Applicable to

• Conditions classifiable to C51-C63

MS-DRG index

Defines the logic of DRG(s) 951 in MDC 23.

Approximate ICD-9-CM (GEMs)

• V16.42 Family history of malignant neoplasm of prostate

Medicare Code Edits (MCE v43.1 (April 2026))

• Unacceptable principal diagnosis: These codes describe a circumstance which influences care but is not a current illness or injury, or capture only an underlying condition, and are unacceptable as principal diagnosis.

Code annotations containing back-references to Z80.42

Back-references to Z80

• Use Additional: Z12 Encounter for screening for malignant neoplasms ("code to identify any family history of malignant neoplasm (Z80.-)")
• Use Additional: Z15 Genetic susceptibility to disease ("code, if applicable, for any associated family history of the disease (Z80-Z84)")

Diagnosis Index entries for Z80.42

• History › family (of) › malignant neoplasm (of) NOS › genital organ › prostate
• History › family (of) › malignant neoplasm (of) NOS › prostate

Nearby codes

• Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
• Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
• Z80.3 Family history of malignant neoplasm of breast
• Z80.4 Family history of malignant neoplasm of genital organs
• Z80.41 Family history of malignant neoplasm of ovary
• Z80.42 Family history of malignant neoplasm of prostate (this code)
• Z80.43 Family history of malignant neoplasm of testis
• Z80.44 Family history of malignant neoplasm of fallopian tube(s)
• Z80.49 Family history of malignant neoplasm of other genital organs
• Z80.5 Family history of malignant neoplasm of urinary tract
• Z80.51 Family history of malignant neoplasm of kidney