Z85.21 Personal history of malignant neoplasm of larynx

Billable ICD-10-CM code, FY2026. Exempt from present-on-admission (POA) reporting.

Applicable to

• Conditions classifiable to C32

Applies from Z85 Personal history of malignant neoplasm

Excludes2 (not included here)

• personal history of benign neoplasm (Z86.01-)
• personal history of carcinoma-in-situ (Z86.00-)

Code first

• any follow-up examination after treatment of malignant neoplasm (Z08)

Use additional code

• code to identify:
• alcohol use and dependence (F10.-)
• exposure to environmental tobacco smoke (Z77.22)
• history of tobacco dependence (Z87.891)
• occupational exposure to environmental tobacco smoke (Z57.31)
• tobacco dependence (F17.-)
• tobacco use (Z72.0)

MS-DRG index

Defines the logic of DRG(s) 011-013 in MDC PRE.

Approximate ICD-9-CM (GEMs)

• V10.21 Personal history of malignant neoplasm of larynx

Medicare Code Edits (MCE v43.1 (April 2026))

• Unacceptable principal diagnosis: These codes describe a circumstance which influences care but is not a current illness or injury, or capture only an underlying condition, and are unacceptable as principal diagnosis.

Code annotations containing back-references to Z85.21

Back-references to Z85

• Use Additional: Z08 Encounter for follow-up examination after completed treatment for malignant neoplasm ("code to identify the personal history of malignant neoplasm (Z85.-)")
• Use Additional: Z15.0 Genetic susceptibility to malignant neoplasm ("code, if applicable, for any personal history of malignant neoplasm (Z85.-)")
• Type 2 Excludes: Z86.0 Personal history of in-situ and benign neoplasms and neoplasms of uncertain behavior ("personal history of malignant neoplasms (Z85.-)")

Diagnosis Index entries for Z85.21

• History › personal (of) › malignant neoplasm (of) › larynx

Nearby codes

• Z85.110 Personal history of malignant carcinoid tumor of bronchus and lung
• Z85.118 Personal history of other malignant neoplasm of bronchus and lung
• Z85.12 Personal history of malignant neoplasm of trachea
• Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
• Z85.20 Personal history of malignant neoplasm of unspecified respiratory organ
• Z85.21 Personal history of malignant neoplasm of larynx (this code)
• Z85.22 Personal history of malignant neoplasm of nasal cavities, middle ear, and accessory sinuses
• Z85.23 Personal history of malignant neoplasm of thymus
• Z85.230 Personal history of malignant carcinoid tumor of thymus
• Z85.238 Personal history of other malignant neoplasm of thymus
• Z85.29 Personal history of malignant neoplasm of other respiratory and intrathoracic organs