Z90.81 Acquired absence of spleen

Billable ICD-10-CM code, FY2026. Exempt from present-on-admission (POA) reporting.

Applies from Z90 Acquired absence of organs, not elsewhere classified

Includes

• postprocedural or post-traumatic loss of body part NEC

Excludes1 (never code together)

• congenital absence - see Alphabetical Index

Excludes2 (not included here)

• postprocedural absence of endocrine glands (E89.-)

MS-DRG index

Defines the logic of DRG(s) 951 in MDC 23.

Approximate ICD-9-CM (GEMs)

• V45.79 Other acquired absence of organ (approximate)

Medicare Code Edits (MCE v43.1 (April 2026))

• Unacceptable principal diagnosis: These codes describe a circumstance which influences care but is not a current illness or injury, or capture only an underlying condition, and are unacceptable as principal diagnosis.

Code annotations containing back-references to Z90.81

Back-references to Z90.81

• Type 1 Excludes: D73.0 Hyposplenism ("postsurgical absence of spleen (Z90.81)")

Back-references to Z90

• Type 2 Excludes: M95 Other acquired deformities of musculoskeletal system and connective tissue ("acquired absence of limbs and organs (Z89-Z90)")
• Use Additional: Z08 Encounter for follow-up examination after completed treatment for malignant neoplasm ("code to identify any acquired absence of organs (Z90.-)")

Diagnosis Index entries for Z90.81

• Absence (of) (organ or part) (complete or partial) › spleen (congenital) › acquired
• Asplenia (congenital) › postsurgical
• Status (post) › splenectomy

Nearby codes

• Z90.72 Acquired absence of ovaries
• Z90.721 Acquired absence of ovaries, unilateral
• Z90.722 Acquired absence of ovaries, bilateral
• Z90.79 Acquired absence of other genital organ(s)
• Z90.8 Acquired absence of other organs
• Z90.81 Acquired absence of spleen (this code)
• Z90.89 Acquired absence of other organs