Z91.048 Other nonmedicinal substance allergy status

Billable ICD-10-CM code, FY2026. Exempt from present-on-admission (POA) reporting.

Applies from Z91 Personal risk factors, not elsewhere classified

Excludes2 (not included here)

• contact with and (suspected) exposures hazardous to health (Z77.-)
• exposure to pollution and other problems related to physical environment (Z77.1-)
• female genital mutilation status (N90.81-)
• occupational exposure to risk factors (Z57.-)
• personal history of physical injury and trauma (Z87.81, Z87.82-)

Applies from Z91.0 Allergy status, other than to drugs and biological substances

Excludes2 (not included here)

• Allergy status to drugs, medicaments, and biological substances (Z88.-)

MS-DRG index

Defines the logic of DRG(s) 951 in MDC 23.

Approximate ICD-9-CM (GEMs)

• V15.09 Other allergy, other than to medicinal agents (approximate)

Medicare Code Edits (MCE v43.1 (April 2026))

• Unacceptable principal diagnosis: These codes describe a circumstance which influences care but is not a current illness or injury, or capture only an underlying condition, and are unacceptable as principal diagnosis.

Code annotations containing back-references to Z91.048

Back-references to Z91.0

• Use Additional: D89.44 Hereditary alpha tryptasemia ("allergy status, other than to drugs and biological substances (Z91.0-)")
• Code Also: Z87.892 Personal history of anaphylaxis ("allergy status, other than to drugs and biological substances (Z91.0-)")
• Type 2 Excludes: Z88 Allergy status to drugs, medicaments and biological substances ("Allergy status, other than to drugs and biological substances (Z91.0-)")

Diagnosis Index entries for Z91.048

• History › personal (of) › allergy (to) › nonmedicinal agents

Nearby codes

• Z91.030 Bee allergy status
• Z91.038 Other insect allergy status
• Z91.04 Nonmedicinal substance allergy status
• Z91.040 Latex allergy status
• Z91.041 Radiographic dye allergy status
• Z91.048 Other nonmedicinal substance allergy status (this code)
• Z91.09 Other allergy status, other than to drugs and biological substances
• Z91.1 Patient's noncompliance with medical treatment and regimen
• Z91.11 Patient's noncompliance with dietary regimen
• Z91.110 Patient's noncompliance with dietary regimen due to financial hardship
• Z91.118 Patient's noncompliance with dietary regimen for other reason