Z92.82 Status post administration of tPA (rtPA) in a different facility within the last 24 hours prior to admission to current facility

Billable ICD-10-CM code, FY2026. Exempt from present-on-admission (POA) reporting.

Code first

• condition requiring tPA administration, such as:
• acute cerebral infarction (I63.-)
• acute myocardial infarction (I21.-, I22.-)

Applies from Z92 Personal history of medical treatment

Excludes2 (not included here)

• postprocedural states (Z98.-)

MS-DRG index

Defines the logic of DRG(s) 065 in MDC 01.

Approximate ICD-9-CM (GEMs)

• V45.88 Status post administration of tPA (rtPA) in a different facility within the last 24 hours prior to admission to current facility

Medicare Code Edits (MCE v43.1 (April 2026))

• Unacceptable principal diagnosis: These codes describe a circumstance which influences care but is not a current illness or injury, or capture only an underlying condition, and are unacceptable as principal diagnosis.

Code annotations containing back-references to Z92.82

Back-references to Z92.82

• Use Additional: I21 Acute myocardial infarction ("status post administration of tPA (rtPA) in a different facility within the last 24 hours prior to admission to current facility (Z92.82)")
• Use Additional: I22 Subsequent ST elevation (STEMI) and non-ST elevation (NSTEMI) myocardial infarction ("status post administration of tPA (rtPA) in a different facility within the last 24 hours prior to admission to current facility (Z92.82)")
• Use Additional: I63 Cerebral infarction ("code, if applicable, to identify status post administration of tPA (rtPA) in a different facility within the last 24 hours prior to admission to current facility (Z92.82)")

Back-references to Z92

• Type 2 Excludes: Z87.7 Personal history of (corrected) congenital malformations ("personal history of medical treatment (Z92.-)")

Diagnosis Index entries for Z92.82

• Administration of tPA (rtPA) in a different facility within the last 24 hours prior to admission to current facility
• Status (post) › administration of tPA (rtPA) in a different facility within the last 24 hours prior to admission to current facility
• Status (post) › tPA (rtPA) administration in a different facility within the last 24 hours prior to admission to current facility
• tPA (rtPA) administration in a different facility within the last 24 hours prior to admission to current facility

Nearby codes

• Z92.26 Personal history of immune checkpoint inhibitor therapy
• Z92.29 Personal history of other drug therapy
• Z92.3 Personal history of irradiation
• Z92.8 Personal history of other medical treatment
• Z92.81 Personal history of extracorporeal membrane oxygenation (ECMO)
• Z92.82 Status post administration of tPA (rtPA) in a different facility within the last 24 hours prior to admission to current facility (this code)
• Z92.83 Personal history of failed moderate sedation
• Z92.84 Personal history of unintended awareness under general anesthesia
• Z92.85 Personal history of cellular therapy
• Z92.850 Personal history of Chimeric Antigen Receptor T-cell therapy
• Z92.858 Personal history of other cellular therapy