B00.81 Herpesviral hepatitis

Billable ICD-10-CM code, FY2026. Acts as a Complication or Comorbidity (CC) as a secondary diagnosis.

Applies from B00 Herpesviral [herpes simplex] infections

Excludes1 (never code together)

• congenital herpesviral infections (P35.2)

Excludes2 (not included here)

• anogenital herpesviral infection (A60.-)
• gammaherpesviral mononucleosis (B27.0-)
• herpangina (B08.5)

MS-DRG index

Defines the logic of DRG(s) 393-395 in MDC 06.

Approximate ICD-9-CM (GEMs)

• 054.71 Visceral herpes simplex (approximate)

Code annotations containing back-references to B00.81

Back-references to B00.81

• Type 1 Excludes: K77 Liver disorders in diseases classified elsewhere ("herpesviral [herpes simplex] hepatitis (B00.81)")

Back-references to B00

• Type 2 Excludes: B10 Other human herpesviruses ("herpes simplex (B00.-)")
• Type 2 Excludes: B10 Other human herpesviruses ("human herpesvirus NOS (B00.-)")
• Type 2 Excludes: B10 Other human herpesviruses ("human herpesvirus 1 and 2 (B00.-)")
• Code Also: D81.82 Activated Phosphoinositide 3-kinase Delta Syndrome [APDS] ("herpes virus infections (B00.-)")
• Code First: H67 Otitis media in diseases classified elsewhere ("viral disease NEC (B00-B34)")

Diagnosis Index entries for B00.81

• Hepatitis › herpesviral
• Herpes, herpesvirus, herpetic › simplex › hepatitis

Nearby codes

• B00.52 Herpesviral keratitis
• B00.53 Herpesviral conjunctivitis
• B00.59 Other herpesviral disease of eye
• B00.7 Disseminated herpesviral disease
• B00.8 Other forms of herpesviral infections
• B00.81 Herpesviral hepatitis (this code)
• B00.82 Herpes simplex myelitis
• B00.89 Other herpesviral infection
• B00.9 Herpesviral infection, unspecified